HUSCAP logo Hokkaido Univ. logo

Hokkaido University Collection of Scholarly and Academic Papers >
Education and Research Programs, Collaborative Project Center >
21st Century COE Program, Neo-Science of Natural History - Origin and Evolution of Natural Diversity >
Neo-Science of Natural History : Integration of Geoscience and Biodiversity Studies >
Proceedings >

Phylogeny and Ontogeny of Regeneration in Vertebrates

Files in This Item:
p45-51-neo-science.pdf1.76 MBPDFView/Open
Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/38490

Title: Phylogeny and Ontogeny of Regeneration in Vertebrates
Authors: Tochinai, Shin Browse this author
Yoshino, Jun Browse this author
Keywords: Phylogeny
Ontogeny
Amphibians
Xenopus laevis
Metamorphosis
Issue Date: 2004
Publisher: Graduate School of Science, Hokkaido University
Citation: Edited by Shunsuke F. Mawatari, Hisatake Okada.
Journal Title: Neo-Science of Natural History: Integration of Geoscience and Biodiversity Studies : Proceedings of International Symposium on "Dawn of a New Natural History - Integration of Geoscience and Biodiversity Studies" March 5-6, 2004, Sapporo
Start Page: 45
End Page: 51
Abstract: This brief paper lays a conceptual link between ontogeny and phylogeny in vertebrate regeneration, inspired by the investigation in an anuran amphibian. Regenerative ability in Xenopus declines most rapidly after the climax of metamorphosis. In order to analyze the cause of this decrease during metamorphosis, we have made comparative experiments in larvae and adults after removing the anterior half of telencephalon. As a result, it was found that brain cells actively proliferated even in non-regenerating adults, just as in regenerating larvae, after partial removal of the telencephalon. Moreover, it was found that even adult-brain-derived dispersed cells reconstituted a subnormal structure of the lost part when transplanted to the partially truncated telencephalon. We consider that it is critical for the ependymal cells to cover the cerebral ventricle at an initial stage of wound healing, for massive organ regeneration, as is the case in larvae. On the other hand, in adults, these cells are strongly stuck in position and unable to move to seal off the exposed ventricle, which probably make the adult brain non-regenerative.
Description: International Symposium on "Dawn of a New Natural History - Integration of Geoscience and Biodiversity Studies". 5-6 March 2004. Sapporo, Japan.
Conference Name: International Symposium on "Dawn of a New Natural History : Integration of Geoscience and Biodiversity Studies"
Conference Place: Sapporo
Type: proceedings
URI: http://hdl.handle.net/2115/38490
Appears in Collections:Neo-Science of Natural History : Integration of Geoscience and Biodiversity Studies > Proceedings

Export metadata:

OAI-PMH ( junii2 , jpcoar_1.0 )

MathJax is now OFF:


 

 - Hokkaido University