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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Dental Medicine / Faculty of Dental Medicine >
Peer-reviewed Journal Articles, etc >
Pain may predict poor prognosis in patients with oral squamous cell carcinoma
| Title: | Pain may predict poor prognosis in patients with oral squamous cell carcinoma |
| Authors: | Sato, Jun Browse this author | | Yamazaki, Yutaka Browse this author | | Satoh, Akira Browse this author | | Onodera-Kyan, Makiko Browse this author | | Abe, Takahiro Browse this author | | Satoh, Takehiko Browse this author | | Notani, Ken-ichi Browse this author | | Kitagawa, Yoshimasa Browse this author |
| Issue Date: | May-2011 |
| Publisher: | Mosby |
| Journal Title: | Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology |
| Volume: | 111 |
| Issue: | 5 |
| Start Page: | 587 |
| End Page: | 592 |
| Publisher DOI: | 10.1016/j.tripleo.2010.11.033 |
| PMID: | 21497734 |
| Abstract: | Objectives: We have previously reported that the histologic mode of invasion of oral squamous cell carcinoma (OSCC) is a significant risk factor for pain. We sought to determine whether pain is a risk factor for poor prognosis in patients with OSCC. Study Design: We evaluated the relationships between overall survival rates (OSRs) and clinicopathological variables, including gender, age, T- and N-stages, pathologic findings, and pain in 109 consecutive patients with untreated OSCC. Results: Of these 109 patients, 40 (37%) reported spontaneous pain. Univariate analysis showed that the OSR of patients with spontaneous pain was significantly lower than that of patients without pain (P = 0.002). Multivariate analysis revealed that spontaneous pain and N-stage were significant independent predictors of OSR. Conclusion: This is the first report showing that spontaneous pain before treatment may be associated with poor prognosis in patients with OSCC. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/45421 |
| Appears in Collections: | 歯学院・歯学研究院 (Graduate School of Dental Medicine / Faculty of Dental Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 佐藤 淳
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