|
Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine >
Peer-reviewed Journal Articles, etc >
A New Variant among Newcastle Disease Viruses Isolated in the Democratic Republic of the Congo in 2018 and 2019
This item is licensed under:Creative Commons Attribution 4.0 International
| Title: | A New Variant among Newcastle Disease Viruses Isolated in the Democratic Republic of the Congo in 2018 and 2019 |
| Authors: | Twabela, Augustin T. Browse this author | | Lam, Thanh Nguyen Browse this author | | Masumu, Justin Browse this author | | Mpoyo, Patrick Browse this author | | Mpiana, Serge Browse this author | | Sumbu, Julienne Browse this author | | Okamatsu, Masatoshi Browse this author →KAKEN DB | | Matsuno, Keita Browse this author →KAKEN DB | | Isoda, Norikazu Browse this author →KAKEN DB | | Zecchin, Bianca Browse this author | | Monne, Isabella Browse this author | | Sakoda, Yoshihiro Browse this author →KAKEN DB |
| Keywords: | new variant | | Newcastle disease virus | | chicken outbreak | | Democratic Republic of the Congo |
| Issue Date: | Feb-2021 |
| Publisher: | MDPI |
| Journal Title: | Viruses-Basel |
| Volume: | 13 |
| Issue: | 2 |
| Start Page: | 151 |
| Publisher DOI: | 10.3390/v13020151 |
| Abstract: | Newcastle disease (ND) is a highly transmissible and devastating disease that affects poultry and wild birds worldwide. Comprehensive knowledge regarding the characteristics and epidemiological factors of the ND virus (NDV) is critical for the control and prevention of ND. Effective vaccinations can prevent and control the spread of the NDV in poultry populations. For decades, the Democratic Republic of the Congo (DRC) has reported the impacts of ND on commercial and traditional poultry farming systems. The reports were preliminary clinical observations, and few cases were confirmed in the laboratory. However, data on the phylogenetic, genetic, and virological characteristics of NDVs circulating in the DRC are not available. In this study, the whole-genome sequences of three NDV isolates obtained using the next-generation sequencing method revealed two isolates that were a new variant of NDV, and one isolate that was clustered in the subgenotype VII.2. All DRC isolates were velogenic and were antigenically closely related to the vaccine strains. Our findings reveal that despite the circulation of the new variant, ND can be controlled in the DRC using the current vaccine. However, epidemiological studies should be conducted to elucidate the endemicity of the disease so that better control strategies can be implemented. |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| Type: | article |
| URI: | http://hdl.handle.net/2115/81219 |
| Appears in Collections: | 獣医学院・獣医学研究院 (Graduate School of Veterinary Medicine / Faculty of Veterinary Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
|
|
