| Title: | Hepatitis E virus infection in pigs : a first report from Zambia |
| Authors: | Chambaro, Herman M. Browse this author |
| Sasaki, Michihito Browse this author →KAKEN DB |
| Muleya, Walter Browse this author |
| Kajihara, Masahiro Browse this author →KAKEN DB |
| Shawa, Misheck Browse this author |
| Mwape, Kabemba E. Browse this author |
| Harima, Hayato Browse this author →KAKEN DB |
| Qiu, Yongjin Browse this author →KAKEN DB |
| Hall, William W. Browse this author |
| Fandamu, Paul Browse this author |
| Squarre, David Browse this author |
| Simulundu, Edgar Browse this author |
| Sawa, Hirofumi Browse this author →KAKEN DB |
| Orba, Yasuko Browse this author →KAKEN DB |
| Keywords: | Hepatitis E virus |
| genotype 3 |
| seroprevalence |
| domestic pig |
| Zambia |
| Issue Date: | 1-Jan-2021 |
| Publisher: | Taylor & Francis |
| Journal Title: | Emerging microbes and infections |
| Volume: | 10 |
| Issue: | 1 |
| Start Page: | 2169 |
| End Page: | 2172 |
| Publisher DOI: | 10.1080/22221751.2021.2002669 |
| Abstract: | While evidence suggests presence of HEV infection in humans in Zambia, currently, there is no information on its occurrence in domestic pigs. Here, we investigated the presence of HEV antibodies and genome in domestic pigs in Zambia. Sera (n = 484) from domestic pigs were screened for antibodies against HEV by ELISA while genome detection in fecal (n = 25) and liver (n = 100) samples from slaughter pigs was conducted using nested RT-PCR assay. Overall, seroprevalence was 47.7% (231/484) while zoonotic genotype 3 HEV RNA was detected in 16.0% (20/125) of slaughtered pigs. This is the first report to highlight occurrence of HEV infection in domestic pigs in Zambia. This finding suggests possible contamination of the pork supply chain. Moreover, there is a potential risk of zoonotic transmission of HEV to abattoir workers, pig farmers and handlers. |
| Type: | article |
| URI: | http://hdl.handle.net/2115/83644 |
| Appears in Collections: | 人獣共通感染症国際共同研究所 (International Institute for Zoonosis Control) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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