2024-03-28T18:13:37Zhttps://eprints.lib.hokudai.ac.jp/dspace-oai/requestoai:eprints.lib.hokudai.ac.jp:2115/838452022-11-17T02:08:08Zhdl_2115_35410hdl_2115_35409Cervical polyps in early pregnancy are a risk factor for late abortion and spontaneous preterm birth: A retrospective cohort studyHirayama, Emi1000090322809Ebina, YasuhikoKato, KeiAkabane-Nakagawa, KinukoOkuyama, Kazuhikoopen accessThis is the peer reviewed version of the following article: Hirayama, E., Ebina, Y., Kato, K., Akabane‐Nakagawa, K. and Okuyama, K. (2021), Cervical polyps in early pregnancy are a risk factor for late abortion and spontaneous preterm birth: A retrospective cohort study. Int J Gynecol Obstet, 156(1): 64-70, which has been published in final form at https://doi.org/10.1002/ijgo.13608. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.cervical insufficiencycervical polyplate abortionretrospective cohort studyrisk factorsspontaneous preterm birth490Objective To determine the association between cervical polyps in early pregnancy and late abortion and spontaneous preterm birth (SPTB). We also aimed to explore the relationship between cervical polyps and cervical insufficiency in the second trimester. Methods We conducted a retrospective cohort study of 2941 singleton pregnant women between January 2010 and December 2015. The frequency of late abortion and SPTB (before 28, 34, or 37 weeks of pregnancy) was compared between the two groups of 142 (4.8%) patients who had cervical polyps early in the pregnancy (P group) and 2799 who did not (non-P group). Multivariate analysis was performed to identify risk factors for late abortion and SPTB. Results The incidence of late abortion and SPTB was significantly higher in the P group than in the non-P group. Cervical polyps in early pregnancy were selected as independent risk factors for late abortion and SPTB before 28, 34, or 37 weeks of pregnancy. The P group had a significantly higher rate of cases requiring therapeutic cervical cerclage than the non-P group. Conclusion Cervical polyps in early pregnancy are risk factors for late abortion and SPTB. They are also associated with the occurrence of cervical insufficiency.John Wiley & Sons2021-01-20engjournal articleAMhttp://hdl.handle.net/2115/83845https://doi.org/10.1002/ijgo.13608334713690020-7292International Journal Of Gynecology & Obstetrics15616470https://eprints.lib.hokudai.ac.jp/dspace/bitstream/2115/83845/1/ebina2021.pdfapplication/pdf518.53 KB2021-01-20