2024-03-29T10:00:35Zhttps://eprints.lib.hokudai.ac.jp/dspace-oai/requestoai:eprints.lib.hokudai.ac.jp:2115/391342022-11-17T02:08:08Zhdl_2115_20044hdl_2115_124Synthesis of 2-Substituted Cyclohexene Derivatives through Cross-Coupling Reactions via π-Allylmetal Intermediate Using N-Heterocyclic Carbenes (NHCs) as LigandsYamazaki, TetsuroSato, YoshihiroN-heterocyclic carbene (NHC)cross-couplingMigita-Kosugi-Stille reactionKumada-Tamao-Coriiu reactionpalladiumnickel499Palladium- or nickel-catalyzed cross-coupling reactions of 2-substituted cyclohexenes, which are generally less reactive than those having no substituent at the C2 position, with organotin reagents (Migita-Kosugi-Stille coupling) or with Grigard reagents (Kumada-Tamao-Corriu coupling) using a NHC as a ligand was investigated. It was found that NHCs are effective as ligands for these reactions, giving the corresponding cross-coupling products in good yields.Georg Thieme Verlag KGJournal Articleapplication/pdfhttp://hdl.handle.net/2115/39134https://eprints.lib.hokudai.ac.jp/dspace/bitstream/2115/39134/1/Sato.pdf0039-78811437-210XAA00855740Synthesis : international journal of methods in synthetic organic chemistry200817283028342008-09enginfo:doi/10.1055/s-2008-1067222© 2008 Georg Thieme Verlag KG.author