2024-03-28T21:20:58Zhttps://eprints.lib.hokudai.ac.jp/dspace-oai/requestoai:eprints.lib.hokudai.ac.jp:2115/639412022-11-17T02:08:08Zhdl_2115_20045hdl_2115_139Copper(I)-Catalyzed Diastereoselective Borylative Exo-Cyclization of Alkenyl Aryl KetonesIto, HajimeYamamoto, EijiKojima, RyotoKubota, Kojiboroncyclizationstereoselective synthesiscoppercatalysis437Copper(I)-catalyzed diastereoselective borylative exo-cyclization of alkenyl ketones with bis(pinacolato)diboron is reported. The reaction of alkenyl aryl ketones under a CuCl/Xantphos catalyst system provides four- or five-membered-ring syn-2-(borylmethyl)cycloalkanol derivatives in good yields with high syn selectivities. The utility of this method is demonstrated by further transformations of the cyclic products.Georg Thieme VerlagJournal Articleapplication/pdfhttp://hdl.handle.net/2115/63941https://eprints.lib.hokudai.ac.jp/dspace/bitstream/2115/63941/1/Ito-S27%282%29.pdf0936-52141437-2096Synlett27022722762016-01enginfo:doi/10.1055/s-0035-1560721author