2024-03-29T04:46:09Zhttps://eprints.lib.hokudai.ac.jp/dspace-oai/requestoai:eprints.lib.hokudai.ac.jp:2115/709102022-11-17T02:08:08Zhdl_2115_20045hdl_2115_139A One-pot Synthesis of Terminal Alkynes from anti-3-Aryl-2,3-dibromopropanoic Acids under Microwave IrradiationKuang, ChunxiangSenboku, HisanoriTokuda, Masaoterminal alkynesmicrowave irradiationA facile one-pot synthesis of terminal alkynes was achieved by microwave irradiation of a mixture of anti-3-aryl-2,3-dibromopropanoic acids, Et3N and DMF and subsequent irradiation in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU). This method requires short reaction time (1–2 min) and gives terminal alkynes in high yields.Chemical Society of JapanJournal Articleapplication/pdfhttp://hdl.handle.net/2115/70910https://eprints.lib.hokudai.ac.jp/dspace/bitstream/2115/70910/1/cl2005.28.pdf0366-70221348-0715AA00603318Chemistry Letters34128292005-01-05enginfo:doi/10.1246/cl.2005.28publisher