2024-03-29T10:51:40Zhttps://eprints.lib.hokudai.ac.jp/dspace-oai/requestoai:eprints.lib.hokudai.ac.jp:2115/787762022-11-17T02:08:08Zhdl_2115_20044hdl_2115_124Cobalt-Catalyzed Allylic Alkylation Enabled by Organophotoredox CatalysisTakizawa, KojiSekino, TomoyukiSato, ShuntaYoshino, TatsuhikoKojima, MasahiroMatsunaga, Shigekiallylic compoundscobaltphotochemistryregioselectivitysynthetic methods460Co-catalyzed allylic substitution reactions have received little attention, arguably because of the lack of any known advantage of Co catalysis over either Rh or Ir catalysis. Described here is a general and regioselective Co-catalyzed allylic alkylation using an in situ catalyst activation by organophotoredox catalysis. This noble-metal-free catalytic system exhibits unprecedentedly high reactivities and regioselectivities for the allylation with an allyl sulfone, for the first time, representing the unique synthetic utility of the Co-catalyzed method compared to the related Rh-and Ir-catalyzed reactions.Wiley-BlackwellJournal Articleapplication/pdfhttp://hdl.handle.net/2115/78776https://eprints.lib.hokudai.ac.jp/dspace/bitstream/2115/78776/1/WoS_90282_Kojima.pdf1433-7851Angewandte chemie-international edition5827919992032019-07-01enginfo:doi/10.1002/anie.201902509This is the peer reviewed version of the following article: K.Takizawa, et al. / Cobalt‐Catalyzed Allylic Alkylation Enabled by Organophotoredox Catalysis. Angewandte chemie-international edition, 58(27), 9199-9203, 2019, which has been published in final form at 10.1002/anie.201902509. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.author