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Abnormal Brain MRI Signals in the Splenium of the Corpus Callosum, Basal Ganglia and Internal Capsule in a Suspected Case with Tuberculous Meningitis
Title: | Abnormal Brain MRI Signals in the Splenium of the Corpus Callosum, Basal Ganglia and Internal Capsule in a Suspected Case with Tuberculous Meningitis |
Authors: | Hirotani, Makoto Browse this author →KAKEN DB | Yabe, Ichiro Browse this author →KAKEN DB | Hamada, Shinsuke Browse this author | Tsuji, Sachiko Browse this author | Kikuchi, Seiji Browse this author | Sasaki, Hidenao Browse this author →KAKEN DB |
Keywords: | tuberculous meningitis | basal ganglia | splenium of the corpus callosum | Internal capsule | allergic tuberculous encephalopathy |
Issue Date: | 17-Apr-2007 |
Publisher: | Japanese Society of Internal Medicine |
Journal Title: | Internal Medicine |
Volume: | 46 |
Issue: | 8 |
Start Page: | 505 |
End Page: | 510 |
Publisher DOI: | 10.2169/internalmedicine.46.6168 |
Abstract: | The patient was a 34-year-old man who visited the hospital with chief complaints of headache, fever, and disturbance of consciousness. In view of his clinical condition, the course of the disease, and results of examination, he was diagnosed with viral meningitis and treated accordingly. However, his clinical condition worsened, and MRI revealed abnormal signals in the splenium of the corpus callosum, in the basal ganglia and in the internal capsule, as well as the presence of severe inflammation in the base of the brain. Since he had a high ADA level in the cerebrospinal fluid and was consequently suspected to have tuberculous meningitis, he was placed on antitubercular agents. Then, his clinical condition began to improve. Additional steroid pulse therapy further improved his condition, and abnormal signals in the splenium of the corpus callosum and the basal ganglia resolved. This patient seems to be a valuable case suggesting that an immune mechanism contributed to the occurrence of central nervous system symptoms associated with tuberculous meningitis. |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/20466 |
Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 矢部 一郎
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