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Volume 37, Number 2 >

MICRONUCLEUS TEST IN MICE FED ON AN IRRADIATED DIET

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Please use this identifier to cite or link to this item:http://doi.org/10.14943/jjvr.37.2.41

Title: MICRONUCLEUS TEST IN MICE FED ON AN IRRADIATED DIET
Authors: ENDOH, Daiji Browse this author
HASHIMOTO, Noriyoshi Browse this author
SATO, Fumiaki Browse this author
KUWABARA, Mikinori Browse this author
Keywords: micronucleus test
erythrocytes
food irradiation
mouse
Issue Date: 20-Jun-1989
Publisher: The Graduate School of Veterinary Medicine
Journal Title: Japanese Journal of Veterinary Research
Volume: 37
Issue: 2
Start Page: 41
End Page: 47
Abstract: A mutagenicity study was carried out in mice fed on a γ-irradiated diet. As an indicator of mutagenic activity, we observed an incidence of micronuclei in erythrocytes. The average body weight of the mice fed on the diet irradiated to dose range of 400-1,000 kGy decreased, and the mice fed on the 800-1,000 kGy-irradiated diet died during the period from 8 to 14 days after the start of feeding. On the other hand, when the mutagenic activity of the irradiated diet was tested by observing occurrence of micronucleus in erythrocytes, no significant increase was recognized. These results indicated that the irradiated diet had no mutagenic activity, even though it possessed a toxic effect on the growth of mice.
Type: bulletin (article)
URI: http://hdl.handle.net/2115/3140
Appears in Collections:Japanese Journal of Veterinary Research > Volume 37, Number 2

Submitter: 獣医学部図書室

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