HUSCAP logo Hokkaido Univ. logo

Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Fisheries Sciences / Faculty of Fisheries Sciences >
Peer-reviewed Journal Articles, etc >

Increase in Deformability of Human Erythrocytes through the Action of β-Lysophospholipid Rich in n-3 Polyunsaturated Fatty Acid Content

Files in This Item:
takahashi_JJOCS47_1313.pdf837.83 kBPDFView/Open
Please use this identifier to cite or link to this item:http://hdl.handle.net/2115/42716

Title: Increase in Deformability of Human Erythrocytes through the Action of β-Lysophospholipid Rich in n-3 Polyunsaturated Fatty Acid Content
Other Titles: n-3系多価不飽和脂肪酸高含有β-リゾリン脂質によるヒト赤血球変形能の増進作用
Authors: Hosokawa, Masashi1 Browse this author →KAKEN DB
Ono, Masayo2 Browse this author
Takahashi, Koretaro3 Browse this author →KAKEN DB
Inoue, Yoshikazu4 Browse this author
Authors(alt): 細川, 雅史1
小野, 雅代2
高橋, 是太郎3
井上, 良計4
Keywords: phospholipids
docosahexaenoic acid
eicosapentaenoic acid
erythrocyte
deformability
Issue Date: 20-Dec-1998
Publisher: 日本油化学会
Journal Title: 日本油化学会誌
Journal Title(alt): Journal of Japan Oil Chemists' Society
Volume: 47
Issue: 12
Start Page: 1313
End Page: 1318
Abstract: Lysophosphatidylcholine (LPC) that binds to docosahexaenoic acid (DHA) at the sn-2 position (β-DHA-LPC) was prepared by the Lipozyme mediated selective partial hydrolysis of DHA-enriched egg yolk lecithin. The β-DHA-LPC was found to be rapidly incorporated into erythrocyte cells and increase their deformability at 5μM/erythrocyte.
リポザイム(ケカビ由来固定化酵素)を用いたドコサヘキサエン酸 (DHA) 強化鶏卵黄ホスファチジルコリン (PC) の選択的部分加水分解反応により,sn-2位にDHAの結合したリゾホスファチジルコリン (β-DHA-LPC) を調製した。このβ-DHA-LPCは,ヒト赤血球懸濁液に対し5μMの濃度においても,速やかにヒト赤血球中に取り込まれ,その変形能を向上させることができることを人工毛細血管モデルにより明らかにした。
Description: 報文
Type: article
URI: http://hdl.handle.net/2115/42716
Appears in Collections:水産科学院・水産科学研究院 (Graduate School of Fisheries Sciences / Faculty of Fisheries Sciences) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 高橋 是太郎

Export metadata:

OAI-PMH ( junii2 , jpcoar )


 

Feedback - Hokkaido University