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Hokkaido University Collection of Scholarly and Academic Papers >
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Peer-reviewed Journal Articles, etc >
Power-Law Stress and Creep Relaxations of Single Cells Measured by Colloidal Probe Atomic Force Microscopy
| Title: | Power-Law Stress and Creep Relaxations of Single Cells Measured by Colloidal Probe Atomic Force Microscopy |
| Authors: | Hiratsuka, Shinichiro Browse this author | | Mizutani, Yusuke Browse this author | | Toda, Akitoshi Browse this author | | Fukushima, Norichika Browse this author | | Kawahara, Koichi Browse this author | | Tokumoto, Hiroshi Browse this author →KAKEN DB | | Okajima, Takaharu Browse this author →KAKEN DB |
| Issue Date: | Aug-2009 |
| Publisher: | Japan Society of Applied Physics |
| Journal Title: | Japanese Journal of Applied Physics |
| Volume: | 48 |
| Issue: | 8 |
| Start Page: | 08JB17 |
| Publisher DOI: | 10.1143/JJAP.48.08JB17 |
| Abstract: | We measured stress and creep relaxations of mouse fibroblast cells arranged and cultured on a microarray, by colloidal probe atomic force microscopy (AFM). A hydrophobic monolayer coating of perfluorodecyltrichlorosilane (FDTS) on the surface of colloidal silica beads significantly reduced the adhesion force of live cells, compared with untreated beads. The rheological behaviors of cells were estimated by averaging several relaxation curves of cells measured by the AFM. Longer-time tailing of both stress and creep relaxation curves followed single power-law behavior over a time scale of 60 s, with exponents in the range 0.1–0.4, varying with cells. The results were in good agreement with previous measurements of the frequency-domain rheology of cells using the force modulation mode. |
| Relation: | http://jjap.jsap.jp/link?JJAP/48/08JB17/ |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/45747 |
| Appears in Collections: | 情報科学院・情報科学研究院 (Graduate School of Information Science and Technology / Faculty of Information Science and Technology) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 岡嶋 孝治
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