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Population Genetics of Trypanosoma evansi from Camel in the Sudan

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Title: Population Genetics of Trypanosoma evansi from Camel in the Sudan
Authors: Salim, Bashir Browse this author
de Meeûs, Thierry Browse this author
Bakheit, Mohammed A. Browse this author
Kamau, Joseph Browse this author
Nakamura, Ichiro Browse this author
Sugimoto, Chihiro Browse this author
Issue Date: 7-Jun-2011
Publisher: Public Library of Science
Journal Title: PLoS Neglected Tropical Diseases
Volume: 5
Issue: 6
Start Page: e1196
Publisher DOI: 10.1371/journal.pntd.0001196
Abstract: Genetic variation of microsatellite loci is a widely used method for the analysis of population genetic structure of microorganisms. We have investigated genetic variation at 15 microsatellite loci of T. evansi isolated from camels in Sudan and Kenya to evaluate the genetic information partitioned within and between individuals and between sites. We detected a strong signal of isolation by distance across the area sampled. The results also indicate that either, and as expected, T. evansi is purely clonal and structured in small units at very local scales and that there are numerous allelic dropouts in the data, or that this species often sexually recombines without the need of the "normal" definitive host, the tsetse fly or as the recurrent immigration from sexually recombined T. brucei brucei. Though the first hypothesis is the most likely, discriminating between these two incompatible hypotheses will require further studies at much localized scales.
Rights: http://creativecommons.org/licenses/by/3.0/
Type: article
URI: http://hdl.handle.net/2115/46839
Appears in Collections:人獣共通感染症リサーチセンター (Research Center for Zoonosis Control) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 杉本 千尋

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