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Nationwide survey on the epidemiology of syringomyelia in Japan
| Title: | Nationwide survey on the epidemiology of syringomyelia in Japan |
| Authors: | Sakushima, Ken Browse this author | | Tsuboi, Satoshi Browse this author | | Yabe, Ichiro Browse this author →KAKEN DB | | Hida, Kazutoshi Browse this author →KAKEN DB | | Terae, Satoshi Browse this author →KAKEN DB | | Uehara, Ritei Browse this author | | Nakano, Imaharu Browse this author | | Sasaki, Hidenao Browse this author →KAKEN DB |
| Keywords: | Syringomyelia | | Epidemiology | | Nationwide survey | | Magnetic Resonance Imaging | | Postal survey | | Ambulatory prevalence |
| Issue Date: | 15-Feb-2012 |
| Publisher: | Elsevier B.V. |
| Journal Title: | Journal of the Neurological Sciences |
| Volume: | 313 |
| Issue: | 1-2 |
| Start Page: | 147 |
| End Page: | 152 |
| Publisher DOI: | 10.1016/j.jns.2011.08.045 |
| PMID: | 21943925 |
| Abstract: | Background: Syringomyelia is a rare disease characterized by abnormal fluid-filled cavities within the spinal cord, and is associated with Chiari malformations, arachnoiditis, or spinal cord tumors. The widespread availability of magnetic resonance imaging (MRI) in Japan has allowed for easy identification of syrinxes. The aim of this study was to survey the clinicoepidemiological characteristics of syringomyelia in Japan. Methods: A 2-stage postal survey was conducted in late 2009. The first survey aimed to estimate the number of patients with syringomyelia, and the second survey aimed to elucidate clinicoepidemiological characteristics. Diagnosis of syringomyelia was based on the findings of MRI or computed tomographic myelography. Results: In the first survey, we received 2133 responses from 2937 randomly selected departments and collected data of 1215 syringomyelia patients (543 men and 672 women). The total response rate for the first survey was 73%. The estimated prevalence of ambulatory syringomyelia patients in Japan was 1.94 per 100 000. In the second survey, the proportion of asymptomatic syringomyelia patients was 22.7%. Chiari type I malformations and idiopathic syringomyelia were the first and second most common etiologies. Conclusions: Our nationwide survey indicated that widespread MRI availability has contributed to the diagnosis of both asymptomatic and idiopathic cases. |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/48600 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 佐久嶋 研
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