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Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Medicine / Faculty of Medicine >
Peer-reviewed Journal Articles, etc >
Clinical features of spinal cord sarcoidosis : analysis of 17 neurosarcoidosis patients
| Title: | Clinical features of spinal cord sarcoidosis : analysis of 17 neurosarcoidosis patients |
| Authors: | Sakushima, Ken Browse this author | | Yabe, Ichiro Browse this author →KAKEN DB | | Nakano, Fumihito Browse this author | | Yoshida, Kazuto Browse this author | | Tajima, Yasutaka Browse this author | | Houzen, Hideki Browse this author | | Maruo, Yasunori Browse this author | | Sasaki, Hidenao Browse this author →KAKEN DB |
| Keywords: | Neurosarcoidosis | | Spinal cord sarcoidosis | | Cerebrospinal fluid | | Angiotensin-converting enzyme |
| Issue Date: | Dec-2011 |
| Publisher: | Springer-Verlag |
| Journal Title: | Journal of Neurology |
| Volume: | 258 |
| Issue: | 12 |
| Start Page: | 2163 |
| End Page: | 2167 |
| Publisher DOI: | 10.1007/s00415-011-6080-3 |
| PMID: | 21553080 |
| Abstract: | The diagnosis of neurosarcoidosis is often difficult; the imaging signs of spinal cord sarcoidosis sometimes mimic those of cervical spondylotic myelopathy, which is common in elderly persons. We examined the characteristics of spinal cord sarcoidosis in Japanese patients with neurosarcoidosis. This case series identified patients with neurosarcoidosis at 4 general hospitals and 1 university hospital from April 1998 to September 2010. All diagnoses were based on the diagnostic criteria proposed by Zajicek et al. Seventeen patients (9 men and 8 women) were involved: 6 patients with spinal cord lesions accompanied by cervical spondylosis, 5 with cerebral lesions, 3 with cranial nerve lesions, 2 with meningitis, and 1, with nerve root lesions. Patients with spinal cord sarcoidosis had a higher onset age, longer duration from onset to diagnosis, reduced leukocytosis in the cerebrospinal fluid (CSF), and lower angiotensin-converting enzyme (ACE) levels in the CSF. The results of this study indicate that diagnosis of spinal cord sarcoidosis requires careful evaluation. |
| Rights: | The original publication is available at www.springerlink.com |
| Type: | article (author version) |
| URI: | http://hdl.handle.net/2115/50771 |
| Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 佐久嶋 研
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