HUSCAP logo Hokkaido Univ. logo

Hokkaido University Collection of Scholarly and Academic Papers >
Graduate School of Engineering / Faculty of Engineering >
Peer-reviewed Journal Articles, etc >

Nanostructure and elastic modulus of single trabecula in bovine cancellous bone

Files in This Item:
120114 JB47-14 3482.pdf1.03 MBPDFView/Open
Please use this identifier to cite or link to this item:

Title: Nanostructure and elastic modulus of single trabecula in bovine cancellous bone
Authors: Yamada, Satoshi Browse this author →KAKEN DB
Tadano, Shigeru Browse this author →KAKEN DB
Fukuda, Sakurako Browse this author
Keywords: Biomechanics
Cancellous bone
Single trabecula
Elastic modulus
X-ray diffraction
Issue Date: 7-Nov-2014
Publisher: Elsevier
Journal Title: Journal of biomechanics
Volume: 47
Issue: 14
Start Page: 3482
End Page: 3487
Publisher DOI: 10.1016/j.jbiomech.2014.09.009
PMID: 25267574
Abstract: We aimed to investigate the elastic modulus of trabeculae using tensile tests and assess the effects of nanostructure at the hydroxyapatite (HAp) crystal scale on the elastic modulus. In the experiments, 18 trabeculae that were at least 3mm in length in the proximal epiphysis of three adult bovine femurs were used. Tensile tests were conducted using a small tensile testing device coupled with microscopy under air-dried condition. The c-axis orientation of HAp crystals and the degree of orientation were measured by X-ray diffraction. To observe the deformation behavior of HAp crystals under tensile loading, the same tensile tests were conducted in X-ray diffraction measurements. The mineral content of specimens was evaluated using energy dispersive X-ray spectrometry. The elastic modulus of a single trabecula varied from 4.5 to 23.6GPa, and the average was 11.5±5.0GPa. The c-axis of HAp crystals was aligned with the trabecular axis and the crystals were lineally deformed under tensile loading. The ratio of the HAp crystal strain to the tissue strain (strain ratio) had a significant correlation with the elastic modulus (r=0.79; P<0.001). However, the mineral content and the degree of orientation did not vary widely and did not correlate with the elastic modulus in this study. It suggests that the strain ratio may represent the nanostructure of a single trabecula and would determine the elastic modulus as well as mineral content and orientation.
Type: article (author version)
Appears in Collections:工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

Submitter: 但野 茂

Export metadata:

OAI-PMH ( junii2 , jpcoar_1.0 )

MathJax is now OFF:


 - Hokkaido University