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Hepatectomy for Hepatocellular Carcinoma with Bile Duct Tumor Thrombus, Including Cases with Obstructive Jaundice

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タイトル: Hepatectomy for Hepatocellular Carcinoma with Bile Duct Tumor Thrombus, Including Cases with Obstructive Jaundice
その他のタイトル: HCC with bile duct tumor thrombus
著者: Orimo, Tatsuya 著作を一覧する
Kamiyama, Toshiya 著作を一覧する
Yokoo, Hideki 著作を一覧する
Wakayama, Kenji 著作を一覧する
Shimada, Shingo 著作を一覧する
Tsuruga, Yosuke 著作を一覧する
Kamachi, Hirofumi 著作を一覧する
Taketomi, Akinobu 著作を一覧する
発行日: 2016年 8月
出版者: Springer
誌名: Annals of surgical oncology
巻: 23
号: 8
開始ページ: 2627
終了ページ: 2634
出版社 DOI: 10.1245/s10434-016-5174-7
抄録: Background: This study aimed to evaluate the short- and long-term outcomes of hepatectomy for hepatocellular carcinoma (HCC) with bile duct tumor thrombus (BDTT), including cases with obstructive jaundice. Methods: The study reviewed 42 HCC patients with BDTT, including six patients who needed preoperative biliary drainage due to obstructive jaundice, and 732 HCC patients without BDTT. The authors analyzed the impact of BDTT on the surgical outcomes and assessed the outcomes of hepatectomy for patients presenting with obstructive jaundice. Results: The HCC patients with BDTT, almost all with stage 3 or 4 disease, had increased alpha-fetoprotein expression, larger tumors, and more portal vein invasion status. The survival of the HCC patients with BDTT was significantly inferior to that of the patients without BDTT (p = 0.0003). Survival did not differ significantly between the HCC patients with BDTT and those without BDTT when the two groups were matched by stage (p = 0.3366). The HCC patients with BDTT who presented with obstructive jaundice demonstrated outcomes similar to those for the HCC patients with BDTT who did not present with obstructive jaundice in terms of the overall survival rate (p = 0.5469). The perioperative outcomes for the HCC patients with BDTT did not depend on the presence or absence of preoperative jaundice. No patients in either BDTT group demonstrated 90-day mortality in this study. Conclusions: Hepatectomy should be considered for HCC patients with BDTT, even for patients with obstructive jaundice, because the surgical outcomes equivalent to those for HCC without BDTT can be achieved.
Rights: The original publication is available at www.springerlink.com
資料タイプ: article (author version)
URI: http://hdl.handle.net/2115/66904
出現コレクション:雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

提供者: 折茂 達也

 

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