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Serological survey of severe fever with thrombocytopenia syndrome virus infection in Sika deer and rodents in Japan

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Please use this identifier to cite or link to this item:http://doi.org/10.14943/jjvr.66.1.21

Title: Serological survey of severe fever with thrombocytopenia syndrome virus infection in Sika deer and rodents in Japan
Authors: Lundu, Tapiwa Browse this author
Yoshii, Kentaro Browse this author →KAKEN DB
Kobayashi, Shintaro Browse this author →KAKEN DB
Morikawa, Shigeru Browse this author →KAKEN DB
Tsubota, Toshio Browse this author →KAKEN DB
Misawa, Naoaki Browse this author
Hayasaka, Daisuke Browse this author
Kariwa, Hiroaki Browse this author →KAKEN DB
Keywords: SFTS
Phlebovirus
Epidemiology
Deer
Rodents
Issue Date: Feb-2018
Journal Title: Japanese Journal of Veterinary Research
Volume: 66
Issue: 1
Start Page: 21
End Page: 28
Abstract: Severe fever with thrombocytopenia syndrome (SFTS) is a newly recognized zoonosis that occurs in China, Japan, and South Korea and is caused by the SFTS virus (SFTSV), which is in the genus Phlebovirus, family Phenuiviridae. Since its discovery in Japan in 2013, SFTS has been reported in the western parts of the country. To elucidate the distribution of SFTSV, we conducted a serological survey of deer and rodents. Serum was screened using enzyme-linked immunosorbent assay (ELISA) and suspected cases were further tested with an indirect immunofluorescence antibody (IFA) assay. Serum samples from 315 deer from Hokkaido (non-endemic area), 41 deer from Miyazaki (endemic area), and 910 rodents from six locations in Japan were tested. Of the 41 deer from Miyazaki, 2 (4.9%) had high ELISA optical density (OD) values (0.1 < OD < 0.3) and a positive IFA result. All of the deer samples from Hokkaido were negative by ELISA (OD < 0.1). No SFTSV-positive rodents were found. Our results indicate that deer in Miyazaki were exposed to SFTSV, unlike deer from Hokkaido (P < 0.05).
Type: bulletin (article)
URI: http://hdl.handle.net/2115/68710
Appears in Collections:Japanese Journal of Veterinary Research > Volume 66 Number 1

Submitter: 獣医学部図書室

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