Title: | Relationships of left ventricular strain and strain rate to wall stress and their afterload dependency |
Other Titles: | Relations of Strain Parameters to Wall Stress |
Authors: | Murai, Daisuke Browse this author |
Yamada, Satoshi Browse this author →KAKEN DB |
Hayashi, Taichi Browse this author |
Okada, Kazunori Browse this author |
Nishino, Hisao Browse this author |
Nakabachi, Masahiro Browse this author |
Yokoyama, Shinobu Browse this author |
Abe, Ayumu Browse this author |
Ichikawa, Ayako Browse this author |
Ono, Kota Browse this author |
Kaga, Sanae Browse this author |
Iwano, Hiroyuki Browse this author →KAKEN DB |
Mikami, Taisei Browse this author →KAKEN DB |
Tsutsui, Hiroyuki Browse this author →KAKEN DB |
Keywords: | Strain |
Strain rate |
Speckle tracking echocardiography |
Wall stress |
Afterload |
Issue Date: | May-2017 |
Publisher: | Springer |
Journal Title: | Heart and vessels |
Volume: | 32 |
Issue: | 5 |
Start Page: | 574 |
End Page: | 583 |
Publisher DOI: | 10.1007/s00380-016-0900-4 |
PMID: | 27734145 |
Abstract: | Whether and how left ventricular (LV) strain and strain rate correlate with wall stress is not known. Furthermore, it is not determined whether strain or strain rate is less dependent on the afterload. In 41 healthy young adults, LV global peak strain and systolic peak strain rate in the longitudinal direction (LS and LSR, respectively) and circumferential direction (CS and CSR, respectively) were measured layer-specifically using speckle tracking echocardiography (STE) before and during a handgrip exercise. Among all the points before and during the exercise, all the STE parameters significantly correlated linearly with wall stress (LS: r = -0.53, p < 0.01, LSR: r = -0.28, p < 0.05, CS in the inner layer: r = -0.72, p < 0.01, CSR in the inner layer: r = -0.47, p < 0.01). Strain more strongly correlated with wall stress than strain rate (r = -0.53 for LS vs. r = -0.28 for LSR, p < 0.05; r = -0.72 for CS vs. r = -0.47 for CSR in the inner layer, p < 0.05), whereas the interobserver variability was similar between strain and strain rate (longitudinal 6.2 vs. 5.2 %, inner circumferential 4.8 vs. 4.7 %, mid-circumferential 7.9 vs. 6.9 %, outer circumferential 10.4 vs. 9.7 %), indicating that the differences in correlation coefficients reflect those in afterload dependency. It was thus concluded that LV strain and strain rate linearly and inversely correlated with wall stress in the longitudinal and circumferential directions, and strain more strongly depended on afterload than did strain rate. Myocardial shortening should be evaluated based on the relationships between these parameters and wall stress. |
Rights: | The final publication is available at link.springer.com |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/70029 |
Appears in Collections: | 北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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