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Quantitative Detection and Fixation of Single and Multiple Gold Nanoparticles on a Microfluidic Chip by Thermal Lens Microscope
Title: | Quantitative Detection and Fixation of Single and Multiple Gold Nanoparticles on a Microfluidic Chip by Thermal Lens Microscope |
Authors: | MAWATARI, Kazuma Browse this author | TOKESHI, Manabu Browse this author →KAKEN DB | KITAMORI, Takehiko Browse this author |
Keywords: | TLM |
Issue Date: | 10-May-2006 |
Publisher: | 日本分析化学会 |
Journal Title: | Analytical Sciences |
Volume: | 22 |
Issue: | 5 |
Start Page: | 781 |
End Page: | 784 |
Publisher DOI: | 10.2116/analsci.22.781 |
Abstract: | A detection and fixation method of single and multiple gold nanoparticles on the wall of a microfluidic channel is demonstrated. A thermal lens microscope (TLM) with continuous-wave excitation (wavelength, 532 nm) and probe (wavelength, 670 nm) laser beams was used to realize the sensitive detection of heat generated by light absorption of individual gold nanoparticles (50 nm in diameter); fixation of the individual nanoparticles was realized simultaneously. The fixation mechanism was investigated and attributed to an absorption-based optical force. In addition to single nanoparticle detection, multiple-nanoparticle detection and fixation was demonstrated. An acceleration of fixation was observed when the number of fixed particles was increased. TLM is expected to be a powerful tool for both the quantitative detection and precise fixation of individual nanoparticles. |
Type: | article |
URI: | http://hdl.handle.net/2115/71669 |
Appears in Collections: | 工学院・工学研究院 (Graduate School of Engineering / Faculty of Engineering) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 渡慶次 学
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