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Serum 25-hydroxyvitamin D-3 levels and poor sleep quality in a Japanese population : the DOSANCO Health Study
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Title: | Serum 25-hydroxyvitamin D-3 levels and poor sleep quality in a Japanese population : the DOSANCO Health Study |
Authors: | Nakamura, Koshi Browse this author →KAKEN DB | Hui, Shu-Ping Browse this author →KAKEN DB | Ukawa, Shigekazu Browse this author →KAKEN DB | Okada, Emiko Browse this author →KAKEN DB | Nakagawa, Takafumi Browse this author | Okabe, Hiroaki Browse this author | Chen, Zhen Browse this author | Miura, Yusuke Browse this author | Chiba, Hitoshi Browse this author →KAKEN DB | Tamakoshi, Akiko Browse this author →KAKEN DB |
Keywords: | 25-Hydroxyvitamin D-3 | Sleep quality | Epidemiology | Japanese |
Issue Date: | May-2019 |
Publisher: | Elsevier |
Journal Title: | Sleep Medicine |
Volume: | 57 |
Start Page: | 135 |
End Page: | 140 |
Publisher DOI: | 10.1016/j.sleep.2019.01.046 |
PMID: | 30981957 |
Abstract: | Objective: The present cross-sectional study investigated the relationship between serum 25-hydroxyvitamin D-3 (25[OH]D-3) levels and the presence of poor sleep quality in a community-based Japanese adult population. Methods: Poor sleep quality, defined as poor subjective sleep quality and/or use of sleep medications, was assessed using a self-administered questionnaire. The prevalence of poor sleep quality was compared among 512 Japanese participants aged 35-79 years, based on serum 25(OH) D-3 levels, which were determined using tandem mass spectrometry. A logistic regression model was used to calculate the odds ratios (ORs) for the presence of poor sleep quality in each group with the highest quartile of 25(OH) D-3 serving as the reference group. Results: Poor sleep quality was reported by 33.2% of the total study population. The prevalence of poor sleep quality was higher in the first quartile group (25[OH] D-3: 2.08-18.13 ng/mL) than in the second, third and fourth quartile groups (18.14-23.07 ng/mL, 23.08-28.32 ng/mL, and 28.33-78.83 ng/mL, respectively). The ORs for poor sleep quality were 1.86 (95% confidence interval, 1.08-3.20) for the first quartile group, 0.73 (0.41-1.29) for the second quartile group, and 0.73 (0.42-1.27) for the third quartile group after adjusting for age, sex, and sociodemographic, lifestyle, physical and environmental factors, while the ORs were 1.68 (0.96-2.95), 0.69 (0.39-1.24), and 0.65 (0.37-1.15) after further adjustment for overall health status and depression status. Conclusions: The first quartile group of serum 25(OH) D-3 was associated with the presence of poor sleep quality. (c) 2019 Elsevier B.V. All rights reserved. |
Rights: | © 2019. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
Type: | article (author version) |
URI: | http://hdl.handle.net/2115/77808 |
Appears in Collections: | 医学院・医学研究院 (Graduate School of Medicine / Faculty of Medicine) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)
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Submitter: 玉腰 暁子
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