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Study of a novel resin cement containing anti-microbial compound CPC-Montmorillonite
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| Title: | Study of a novel resin cement containing anti-microbial compound CPC-Montmorillonite |
| Other Titles: | CPCモンモリロナイトを含む新規歯科用レジンセメントに関する検討 |
| Authors: | 山本, 裕也 Browse this author |
| Keywords: | Secondary caries | | Biofilm | | Resin cement | | Montmorillonite | | Cetylpyridinium |
| Issue Date: | 25-Mar-2021 |
| Publisher: | Hokkaido University |
| Abstract: | Objective: The aim of this study was to evaluate the mechanical property, bonding performance and anti-microbial activity of a novel resin cement containing montmorillonite modified Cetylpyridinium chloride (CPC-Mont), and to determine the optimal particle size and concentration of CPC-Mont to be lorded to the resin cement. Materials and methods: Montmorillonite filler modified CPC with a median diameter of 30μm and 7μm were prepared, and they lorded to a resin cement at concentrations of 2, 3, 4, 5, 7.5 wt.%. Mechanical property and bonding performance of the resin cements were evaluated by 3 point bending test and micro-tensile bond strength test. The amount of CPC released from the resin disks were quantified using a UV-vis recording spectrophotometer. The anti-biofilm activity was also studied using scanning electron microscope. Results: Mechanical property and bonding performance of the resin cement decreased with lording 30μm CPC-Mont, but no reduction was observed with lording 7μm CPC-Mont. Although CPC release was decreased as the immersion period passed, 5 and 7.5 wt.% CPC-Mont resin cement inhibited biofilm formation for 30 days. Conclusions: The lording of CPC-Mont with a median diameter of 7μm at concentrations of 5 to 7.5 wt.% to resin cement was effective in achieving continuous anti-biofilm activity while maintaining the mechanical property and bonding performance. |
| Conffering University: | 北海道大学 |
| Degree Report Number: | 甲第14529号 |
| Degree Level: | 博士 |
| Degree Discipline: | 歯学 |
| Examination Committee Members: | (主査) 教授 吉田 靖弘, 教授 井上 哲, 教授 佐野 英彦 |
| Degree Affiliation: | 歯学院（口腔医学専攻） |
| Type: | theses (doctoral) |
| URI: | http://hdl.handle.net/2115/81199 |
| Appears in Collections: | 課程博士 (Doctorate by way of Advanced Course) > 歯学院(Graduate School of Dental Medicine)
学位論文 (Theses) > 博士 （歯学）
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