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Molluscum contagiosum of the corneal limbus in an AIDS patient : a clinicopathological case report

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Title: Molluscum contagiosum of the corneal limbus in an AIDS patient : a clinicopathological case report
Authors: Fujita, Yukihiro Browse this author
Kase, Satoru Browse this author →KAKEN DB
Ishida, Susumu Browse this author →KAKEN DB
Keywords: Molluscum contagiosum
Optical coherence tomography
Issue Date: 21-Feb-2022
Publisher: BioMed Central
Journal Title: BMC ophthalmology
Volume: 22
Issue: 1
Start Page: 83
Publisher DOI: 10.1186/s12886-022-02312-2
Abstract: Background Molluscum contagiosum, a pox virus infection, is likely to occur in the eyelid skin; however, corneal involvements by molluscum lesions are extremely rare. We report a case of molluscum contagiosum arising in the corneal limbus in an untreated AIDS patient, together with anterior segment optical coherence tomography (OCT) findings and histopathology of the excised tumor. Case presentation A 46-year-old man with AIDS was referred to our department for the management of an ocular lesion. Blood tests revealed an extremely low CD4+ T-cell count of 11 cells/mu L, being strongly positive for anti-HIV antibody (591.36 S/CO) with a high copy number of HIV RNA (8070.0 x 100 copy/mL). Slit-lamp examination of his right eye showed a white nodule at the lower limbus. Anterior segment OCT findings of the nodule revealed a highly reflective elevated lesion, which was considered to involve the Bowman layer. The nodular lesion was excised from the limbus including the superficial corneal stroma, and then processed for histologic examination. Histopathology of the excised lesion showed acanthotic corneal epithelium containing swollen cells with eosinophilic inclusions known as molluscum bodies. He was diagnosed with molluscum contagiosum. Conclusions Anterior segment OCT findings provide useful information for morphological evaluations of and preoperative strategies against molluscum contagiosum.
Type: article
Appears in Collections:北海道大学病院 (Hokkaido University Hospital) > 雑誌発表論文等 (Peer-reviewed Journal Articles, etc)

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