Japanese Journal of Veterinary Research

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Cover Figure
Programmed death-1 (PD-1)/ PD-ligand 1 (PD-L1) pathway and prostaglandin E2 (PGE2) involve in the immunosuppression during Mycoplasma bovis infection. This study showed that the bacterial loads in cattle treated with PD-L1 antibody and COX-2 inhibitor were decreased. The results suggest that the combination of anti-PD-L1 antibody with a COX-2 inhibitor is a candidate for therapeutic applications to treat M. bovis infection.
See the article by Shinya Goto et al. on page 77.

Volume 68 Number 2    (2020-05 issued)


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