Japanese Journal of Veterinary Research;Volume 2, Number 2

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THERAPEUTIC TREATMENTS IN CANINE DISTEMPER WITH CHLOROMYCETIN AND AUREOMYCIN

NAKAMURA, Ryoichi;SONODA, Mitsuo;TOO, Kimehiko;KIKUCHI, Tetsuo;NISHIOKA, Naruhito

Permalink : http://hdl.handle.net/2115/1655
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Abstract

The workers tried to make therapeutic experiments in complicated canine distemper with oral administration of chloromycetin and aureomycin. The results thus obtained may be summarized as follows. 1. Chloromycetin was an effective agent in controlling the secondary pneumonia and gastroenteritis of canine distemper. It was administered at the rate of 25 to 50 mg/kg with a mean of 30.3 mg/kg of body weight in divided doses to 4 times per day for 2 to 5 days. 2. Aureomycin was also an effective agent for the secondary invaders in canine distemper as was chloromycetin. The dosage schedules ranged from 25 to 50 mg/kg with a mean of 31.3 mg/kg of body weight divided into 4 times per day for 2 to 5 days. 3. Chloromycetin and aureomycin have no effectiveness for the nervous type of canine distemper insofar as shown in the present experiments. 4. Topical use of aureomycin ointment 1 or 2 times per day for 2 to 4 days has a dramatic value for conjunctivitis and pustular dermatitis accompanying canine distemper. 5. For the treatments in complicated canine distemper, there is needed also symptomatic therapies. 6. By MULLER and S. S. media in feces and nasal discharges there were found coil and proteus groups which seemed to have no pathogens ; other microorganisms were not found. Researches on the secondary invaders using other cultures are now in progress in our clinic. 7. Varieties of hematological findings, especially in neutrophiles and eosinophiles, have important significance in observing the severity of diseases and to make prongnoses.

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