Japanese Journal of Veterinary Research;Volume 10, Number 2

FONT SIZE:  S M L

STUDIES ON HEMOLYTIC ESCHERICHIA COLI OF O 139 A LETHAL SUBSTANCE FOUND IN PROLONGED CULTURE FILTRATES

INUKAI, Yoshikazu;KODAMA, Hirohide;HAGA, Tadashi

Permalink : http://hdl.handle.net/2115/1760
KEYWORDS : 

Abstract

A lethal substance for mice, found in prolonged culture filtrates of a hemolytic strain of Escherichia coli of O 139 derived from the intestine of a pig which suffered from edema disease, was isolated by chromatography on DEAE-cellulose column. So-called endotoxin, contained in young cells of the organisms, was also isolated by the same means. Both toxic substances behaved similarly on DEAE-cellulose column. Besides, they, when injected to mice, induced similar symptoms and each reacted against homologous anti-O serum. From these facts, identity of these two toxic substances would be emphasized.

FULL TEXT:PDF