Japanese Journal of Veterinary Research;Volume 11, Number 4

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REGIONAL DIFFERENCES IN THE APPEARANCE OF VARIOUS CELLS IN THE MOUSE LYMPH NODES

SUGIMURA, Makoto;TAKAHATA, Kurahiko;KUDO, Norio;FURUHATA, Kitao

Permalink : http://hdl.handle.net/2115/1783
JaLCDOI : 10.14943/jjvr.11.4.123

Abstract

An attempt was made to clarify the cell types and regional differences in the appearance of various cells found in 263 lymph nodes, obtained from 13 different locations in 20 mature mice. By histological and histochemical procedures, small lymphocytes, large lymphocytes, plasma cells, mast cells, PAS positive cells of four types, extramedullary myelopoiesis and adipose tissues were distinguished in the mouse lymph nodes. Regional differences were clarified as to appearance of large lymphocytes, plasma cells, mast cells, PAS positive cells of type IV, having glycolipin which shows lipofuscin-like nature, and adipose tissues in the medulla. Based on these findings, the mouse lymph nodes were classified in five groups. First group (submandibular and cervical nodes) : Many plasma cells. Second group (superficial axillary, deep axillary, inguinal and popliteal nodes) : Many mast cells. Third group (iliac, caudal, renal and mediastinal nodes) : Intermediate type. Adipose tissue is often found in renal and mediastinal nodes. Fourth group (tracheobronchial node) : Also intermediate type. However, large lymphocytes are fairly frequently observed. Fifth group (mesenteric and coeliac nodes) : Very few plasma and mast cells. But, many PAS positive cells of type IV.

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