Japanese Journal of Veterinary Research;Volume 15, Number 4

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CRYSTALLINE INCLUSIONS IN ENDOTHELIAL CELLS OF POST-CAPILLARY VENULES OF MOUSE LYMPH NODES

SUGIMURA, Makoto;FURUHATA, Kitao;KUDO, Norio;MIFUNE, Yoshikatsu

Permalink : http://hdl.handle.net/2115/1886
JaLCDOI : 10.14943/jjvr.15.4.153

Abstract

The crystalline inclusions in the post-capillary venules of mouse lymph nodes were observed by use of electron microscopy with special reference to their origin and fate. The inclusions are surrounded by a limiting membrane, spherical in shape and approximately 0.5〜2μ in size. One inclusion usually has one crystal, but sometimes several crystals. The three dimensional forms of the crystals appear to be nearly cubic. It is morphologically clear that the crystalline inclusions are closely related to the rough-surfaced endoplasmic reticulum, the Golgi complex, multivesicular bodies, lysosome-like dense bodies and vesicles with a fine granular matrix. It is suggested that the endothelial cells synthesize a substance which is condensed in the Golgi complex and multivesicular bodies, and then the condensed fine granular substance is released into the basal and intercellular spaces of the endothelium. The crystalline inclusions are presumed to be a storage form of a substance synthesized by the endothelial cells.

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