Japanese Journal of Veterinary Research;Volume 46, Number 4

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Antigenic and genetic analyses of H5 influenza viruses isolated from ducks in Asia

IMAI, Masaki;TAKADA, Ayato;OKAZAKI, Katsunori;KIDA, Hiroshi

Permalink : http://hdl.handle.net/2115/2717
JaLCDOI : 10.14943/jjvr.46.4.171
KEYWORDS : Duck;Hemagglutinin;H5;Influenza virus

Abstract

The hemagglutinin (HA) of six H5 influenza virus strains isolated from ducks in Japan and China in 1976 to 1996 were analyzed antigenically and genetically. Antigenic analysis using a panel of monoclonal antibodies revealed that the HA of H5 influenza viruses isolated from ducks are antigenically closely related to each other. Phylogenetic analysis indicates that the isolates from ducks in Hokkaido were derived from an ancestor common with the highly pathogenic isolates from chickens and humans in Hong Kong in 1997.

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