Japanese Journal of Veterinary Research;Volume 66 Number 4

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Complete atrioventricular block due to primary cardiac lymphoma in a dog

Sasaki, Takafumi;Kimura, Yusuke;Imai, Tomoko;Machida, Noboru

Permalink : http://hdl.handle.net/2115/72024
JaLCDOI : 10.14943/jjvr.66.4.305
KEYWORDS : complete atrioventricular block;dog;primary cardiac lymphoma

Abstract

A histological investigation of the atrioventricular (AV) conduction system was performed in an 11-year-old golden retriever with complete AV block. Necropsy revealed a large grayish-white mass with an irregular shape located in the AV junctional area of the lateral aspect of the left heart. Histological and immunohistochemical examinations provided a diagnosis of primary cardiac lymphoma of T-cell origin. Histological findings in the AV conduction system included severe infiltration of neoplastic lymphoid cells into the AV nodal region, causing total destruction of the AV node. Similarly, neoplastic cell infiltration had entrapped the AV bundle, causing various degrees of degeneration, atrophy, and loss of conduction fibers. Such neoplastic lesions of the AV conduction system were associated with complete AV block.

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