Japanese Journal of Veterinary Research;Volume 67 Number 3

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Neuromuscular and vascular hamartoma of the cecum in a dog

Yamashita, Misaki;Sunden, Yuji;Osaki, Tomohiro;Tsuka, Takeshi;Morita, Takehito

Permalink : http://hdl.handle.net/2115/75492
JaLCDOI : 10.14943/jjvr.67.3.247
KEYWORDS : cecum;dog;NMVH

Abstract

Neuromuscular and vascular hamartoma (NMVH) is a rare non-epithelial hamartoma of the intestine in humans that is characterized by proliferation of smooth muscle, blood vessels and bundles of unmyelinated nerve fibers in the intestinal submucosa. Here, we describe a case in which a mass lesion in the cecum of an 8-year-old male West Highland White Terrier dog. The mass caused an inversion of the cecum, which was surgically removed. The mass was found in the muscle layer of the inverted cecum, and on histology was composed of a proliferation of mainly spindle-shaped cells with fibrillar cytoplasm, vascular structures, and bundles of unmyelinated nerve fibers. These features of the mass are consistent with those described for NMVH in humans.

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