Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins

Ohno, Yusuke; Kihara, Akio; Sano, Takamitsu; Igarashi, Yasuyuki

Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins

Ohno, Yusuke; Kihara, Akio; Sano, Takamitsu et al.

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2006, 1761(4), 474-483

Permalink : https://hdl.handle.net/2115/14509

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アクセス権	open access
URI	https://hdl.handle.net/2115/14509
タイトル	Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins
著者	Ohno, Yusuke ; Kihara, Akio ; Sano, Takamitsu ; Igarashi, Yasuyuki
著者名 Ohno, Yusuke
e-Rad_Researcher 50333620 著者名 Kihara, Akio
e-Rad_Researcher 10399967 著者名 Sano, Takamitsu
e-Rad_Researcher 70091965 著者名 Igarashi, Yasuyuki
言語	英語
キーワード	DHHC cysteine-rich domain
	Palmitoylation
	Protein acyltransferase
発行日	2006-04
出版者	Elsevier
収録物名	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
巻(号)	1761(4)
ページ	474-483
抄録	Increasing evidence indicates that DHHC cysteine-rich domain-containing proteins (DHHC proteins) are protein acyltransferases. Although multiple DHHC proteins are found in eukaryotes, characterization has been examined for only a few. Here, we have cloned all the yeast and human DHHC genes and investigated their intracellular localization and tissue-specific expression. Most DHHC proteins are localized in the ER and/or Golgi, with a few localized in the plasma membrane and one in the yeast vacuole. Human DHHC mRNAs also differ in their tissue-specific expression. These results may provide clues to aid in discovering the specific function(s) of each DHHC protein.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
PISSN	1388-1981
関連情報	PMID 16647879
関連情報	URI http://www.sciencedirect.com/science/journal/13881981
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.bbalip.2006.03.010