Multidirectional flexibility analysis of anterior and posterior lumbar artificial disc reconstruction: in vitro human cadaveric spine model.

Kotani, Yoshihisa; Cunningham, Bryan W.; Abumi, Kuniyoshi; Dmitriev, Anton E.; Hu, Niabin; Ito, Manabu; Shikinami, Yasuo; McAfee, Paul C.; Minami, Akio

Multidirectional flexibility analysis of anterior and posterior lumbar artificial disc reconstruction: in vitro human cadaveric spine model.

Kotani, Yoshihisa; Cunningham, Bryan W.; Abumi, Kuniyoshi et al.

European Spine Journal, 2006, 15(10), 1511-1520

Permalink : https://hdl.handle.net/2115/14768

このアイテムのアクセス数:2,174件（2026-02-12 12:51 集計）

閲覧可能ファイル

ファイル	フォーマット	サイズ	閲覧回数	説明
ESJ	pdf	1.22 MB	2,558

論文情報

ファイル出力 EndNote Basic出力 Mendeley出力

アクセス権	open access
URI	https://hdl.handle.net/2115/14768
タイトル	Multidirectional flexibility analysis of anterior and posterior lumbar artificial disc reconstruction: in vitro human cadaveric spine model.
著者	Kotani, Yoshihisa ; Cunningham, Bryan W. ; Abumi, Kuniyoshi ; Dmitriev, Anton E. ; Hu, Niabin ; Ito, Manabu ; Shikinami, Yasuo ; McAfee, Paul C. ; Minami, Akio
著者名 Kotani, Yoshihisa
著者名 Cunningham, Bryan W.
著者名 Abumi, Kuniyoshi
著者名 Dmitriev, Anton E.
著者名 Hu, Niabin
著者名 Ito, Manabu
著者名 Shikinami, Yasuo
著者名 McAfee, Paul C.
e-Rad_Researcher 20133738 著者名 Minami, Akio
言語	英語
キーワード	Artificial intervertebral disc
	Lumbar spine
	Biomechanics
発行日	2006
出版者	Springer Berlin / Heidelberg
収録物名	European Spine Journal
巻(号)	15(10)
ページ	1511-1520
抄録	The in vitro multidirectional flexibility analysis was conducted to investigate the initial biomechanical effect of biomimetic artificial intervertebral disc replacement from either anterior or posterior approach in a cadaveric lumbosacral spine model. Two designs of anterior total and posterior subtotal artificial discs were developed using bioactive three-dimensional fabric and bioresorbable hydroxyapatite/poly-l-lactide material (3DF disc). Both models were designed to obtain the stable interface bonding to vertebral endplates with maximum surface area occupation. Using seven cadaveric lumbosacral spines, the following three anterior reconstruction methods were sequentially performed at L4–5 level: anterior 3DF disc replacement; anterior BAK cages (BAK); and posterior pedicle screw fixation and anterior BAK cages combined (BAK + PS). The L2–3 level received two methods of posterior reconstructions: subtotal 3DF disc replacement (two implants), and posterior interbody cages and pedicle screw fixation (PLIF). Six unconstrained pure moments were applied and three-dimensional segmental motions were measured with an optoelectronic motion measurement system. The center of rotation (COR) calculation was conducted radiographically using flexion-extension films. Both anterior and posterior 3DF replacements statistically demonstrated equivalent range of motions (ROMs) in all loading modes compared to intact segment. Anterior BAK, BAK + PS, and PLIF demonstrated significantly lower ROMs when compared to intact and 3DF groups (P<0.05). The 3DF reconstruction tended to realign the COR to the posterior third or surrounding position at the operative disc level. The stand-alone lumbar 3DF disc replacement demonstrated biomechanical characteristics nearly equivalent to the intact spinal segments even through anterior or posterior approach in vitro, suggesting an excellent clinical potential.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	The original publication is available at www.springerlink.com
PISSN	0940-6719
EISSN	1432-0932
関連情報	PMID 16552532
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1007/s00586-006-0086-z