A new dynamic myocardial phantom for the assessment of left ventricular function by gated single-photon emission tomography.

Kubo, Naoki; Morita, Koichi; Katoh, Chietsugu; Shiga, Tohru; Konno, Masanori; Tsukamoto, Eriko; Morita, Yutaka; Tamaki, Nagara

A new dynamic myocardial phantom for the assessment of left ventricular function by gated single-photon emission tomography.

Kubo, Naoki; Morita, Koichi; Katoh, Chietsugu et al.

European Journal of Nuclear Medicine and Molecular Imaging, 2000, 27(10), 1525-1530

Permalink : https://hdl.handle.net/2115/14887

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アクセス権	open access
URI	https://hdl.handle.net/2115/14887
タイトル	A new dynamic myocardial phantom for the assessment of left ventricular function by gated single-photon emission tomography.
著者	Kubo, Naoki ; Morita, Koichi ; Katoh, Chietsugu ; Shiga, Tohru ; Konno, Masanori ; Tsukamoto, Eriko ; Morita, Yutaka ; Tamaki, Nagara
e-Rad_Researcher 80241389 著者名 Kubo, Naoki
著者名 Morita, Koichi
著者名 Katoh, Chietsugu
著者名 Shiga, Tohru
著者名 Konno, Masanori
著者名 Tsukamoto, Eriko
著者名 Morita, Yutaka
著者名 Tamaki, Nagara
言語	英語
キーワード	Myocardium
	Phantom
	Wall motion
	Single-photon emission tomography
発行日	2000-09
収録物名	European Journal of Nuclear Medicine and Molecular Imaging
巻(号)	27(10)
ページ	1525-1530
抄録	Gated myocardial perfusion single-photon emission tomography (SPET) has been used for the measurement of left ventricular (LV) function and validated by means of comparison with other imaging modalities. We have designed a new dynamic myocardial phantom in order to validate the LV function as assessed by the use of gated myocardial perfusion SPET. The phantom consists of two half-ellipsoids (an endocardial surface and an epicardial surface) and a thorax. The myocardial space is filled with a radioactive solution. The endocardial surface moves continuously towards and away from the epicardial surface in the longitudinal axis to vary the LV volume [143 ml at end-diastole (ED), 107 ml at end-systole (ES)] and thickness (apex 8 mm at ED and 26 mm at ES, midplane 8 mm). The mean values of wall motion (WM) for the apical midplane region and the basal midplane region were 5 mm and 2 mm, respectively. Gated myocardial SPET was performed during 8 and 16 intervals. These projection data sets were processed using a Butterworth filter with an order of 5 and a critical frequency of 0.34 cycles/cm. LV function was calculated using the quantitative gated SPET (QGS) algorithm. The LV function values estimated by gated SPET during 16 intervals [22% for ejection fraction (EF), 3.7 mm for WM of the apical midplane, 1.7 mm for WM of the basal midplane] closely resembled actual LV functions [25% for EF, 5 mm for WM of the apical midplane, 2 mm for WM of the basal midplane]. However, the estimated values during 8 intervals were smaller than those during 16 intervals (19% for EF, 3.3 mm for WM of the apical-midplane, 1.1 mm for WM of the basal-midplane). The estimated LV volumes closely correlated with the actual volumes (r=0.99 for 16 intervals, r=0.95 for 8 intervals). Utilizing this phantom, LV function estimated using gated myocardial SPET can be compared with actual values.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	The original publication is available at www.springerlink.com
PISSN	1619-7070
EISSN	1619-7089
関連情報	PMID 11083542
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1007/s002590000318