Complete cDNA Sequences and Phylogenetic Analyses of the Th1 and Th2 Cytokines of the Bactrian Camel (Camelus bactrianus)

Odbileg, Raadan; Purevtseren, Byambaa; Batsukh, Zayat et al.

Journal of Veterinary Medical Science, 2006, 68(9), 941-946

Permalink : https://hdl.handle.net/2115/15849

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アクセス権
open access
URI
https://hdl.handle.net/2115/15849
タイトル
Complete cDNA Sequences and Phylogenetic Analyses of the Th1 and Th2 Cytokines of the Bactrian Camel (Camelus bactrianus)
著者
Odbileg, Raadan ; Purevtseren, Byambaa ; Batsukh, Zayat ; Konnai, Satoru ; Ohashi, Kazuhiko ; Onuma, Misao
著者名
Odbileg, Raadan
著者名
Purevtseren, Byambaa
著者名
Batsukh, Zayat
e-Rad_Researcher
40396304
著者名
Konnai, Satoru
e-Rad_Researcher
90250498
著者名
Ohashi, Kazuhiko
e-Rad_Researcher
70109510
著者名
Onuma, Misao
言語
英語
キーワード
camel cytokines
cDNA sequence
phylogenetic analysis
Th1
Th2
発行日
2006-09
出版者
Japanese Society of Veterinary Science
収録物名
Journal of Veterinary Medical Science
巻(号)
68(9)
ページ
941-946
抄録
The complementary DNAs of the Th1 (IL-2, IL-12p35, and IFN-γ) and Th2 (IL-4, IL-10 and IL-13) cytokine genes of the bactrian camel (Camelus bactrianus) were cloned, sequenced, and analyzed. IL-2, IL-4, IL-10, IL-12p35, IL-13, and IFN-γ were found to have 465, 402, 537, 669, 411, and 501 bp length open reading frames with 154, 133, 178, 222, 136, and 166 amino acid encodings, respectively. The homology ranged from 58.8% to 100% between the nucleotide sequences of the camel cytokine genes and the published sequences of other mammalian genes, including the llama, pig, cow, horse, human, and mouse. The cDNA had highest homology with orders Artiodactyla (pigs and cattle) and Perissodactyla (horses), especially to the recently cloned llama sequences.
資源タイプ
学術雑誌論文
出版タイプ
Accepted Manuscript
PISSN
0916-7250
EISSN
1347-7439
関連情報
PMID
17019063
関連情報 (isVersionOf)
出版社版DOI
https://doi.org/10.1292/jvms.68.941