Dietary branched-chain amino acids suppress the expression of pancreatic amylase mRNA in rats.

Hashimoto, Naoto; Hara, Hiroshi

Bioscience Biotechnology and Biochemistry, 2004, 68(5), 1067-1072

Permalink : https://hdl.handle.net/2115/15857

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アクセス権
open access
URI
https://hdl.handle.net/2115/15857
タイトル
Dietary branched-chain amino acids suppress the expression of pancreatic amylase mRNA in rats.
著者
著者名
Hashimoto, Naoto
e-Rad_Researcher
70198894
著者名
Hara, Hiroshi
言語
英語
キーワード
pancreatic amylase
dietary branched-chain amino acids
dietary carbohydrate
rat
発行日
2004-05
出版者
Japan Society for Bioscience, Biotechnology, and Agrochemistry
収録物名
Bioscience Biotechnology and Biochemistry
巻(号)
68(5)
ページ
1067-1072
抄録
Regulators for pancreatic amylase were examined. Rats were fed ad libitum a 20% amino acid (AA) mixture diet (Con), a 60% AA diet (HA), a branched-chain amino acid (BCAA)-rich diet (BC), or a diet supplemented with AA other than BCAA (OA) for 7 d, or fed the Con, HA, BC diets or diets supplemented with individual BCAA. Activity and mRNA levels of pancreatic amylase in the BC and HA groups were lower than those in the Con and OA groups. Leucine and isoleucine contributed to these effects of the BC diet. The mRNA levels correlated with individual pancreatic BCAA concentrations but not with plasma insulin level. In conclusion, dietary BCAA, especially leucine and isoleucine, may reduce amylase mRNA and activity in rats.
資源タイプ
学術雑誌論文
出版タイプ
Version of Record
PISSN
0916-8451
EISSN
1347-6947
関連情報
PMID
15170111
URI
http://www.jstage.jst.go.jp/
関連情報 (isIdenticalTo)
出版社版DOI
https://doi.org/10.1271/bbb.68.1067