open access

https://hdl.handle.net/2115/17120

Correlations between neuropsychological test results and P300 latency during silent-count and button-press tasks in post-traumatic brain injury patients.

英語

Post-traumatic brain injury patients

2006-11

Elsevier Ltd

Journal of Clinical Neuroscience

13(9)

917-922

To evaluate the correlations between memory function and intelligence and event-related potential, the P300 component for different tasks was studied for 30 post-traumatic brain injury patients (mean age 31.6 ± 13.7 years; 23 male and 7 female). Memory function, intelligence, and depression were measured by using the Mini-Mental State Examination, the revised Wechsler Adult Intelligence Scale and the Self-Rating Depression Scale, respectively. P300 latency was measured during silent-count and button-press tests at three midline scalp (Fz, Cz, and Pz) sites for all subjects by using an auditory ‘odd-ball’ paradigm. Neuropsychological memory score was predicted by intelligence score, but neurophysiological P300 latency was predicted by memory score for the silent-count test and by intelligence score for the button-press test. These results show that the P300 event-related potential component is sensitive to the diverse nature of cognitive deficits in post-traumatic brain injury patients during different types of discrimination tasks. However, future research is necessary to replicate and extend these findings.

学術雑誌論文

Accepted Manuscript

0967-5868