Molecular epidemiology of adenoviral conjunctivitis in Hanoi, Vietnam

Jin, Xue-Hai; Ishiko, Hiroaki; Nguyen, Thanh Ha; Ohguchi, Takeshi; Akanuma, Masataka; Aoki, Koki; Ohno, Shigeaki

Molecular epidemiology of adenoviral conjunctivitis in Hanoi, Vietnam

Jin, Xue-Hai; Ishiko, Hiroaki; Nguyen, Thanh Ha et al.

American Journal of Ophthalmology, 2006, 142(6), 1064-1066

Permalink : https://hdl.handle.net/2115/17151

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アクセス権	open access
URI	https://hdl.handle.net/2115/17151
タイトル	Molecular epidemiology of adenoviral conjunctivitis in Hanoi, Vietnam
著者	Jin, Xue-Hai ; Ishiko, Hiroaki ; Nguyen, Thanh Ha ; Ohguchi, Takeshi ; Akanuma, Masataka ; Aoki, Koki ; Ohno, Shigeaki
著者名 Jin, Xue-Hai
著者名 Ishiko, Hiroaki
著者名 Nguyen, Thanh Ha
著者名 Ohguchi, Takeshi
著者名 Akanuma, Masataka
著者名 Aoki, Koki
著者名 Ohno, Shigeaki
言語	英語
キーワード	adenovirus
	conjunctivitis
	molecular epidemiology
	real-time PCR
発行日	2006-12
出版者	Elsevier Inc.
収録物名	American Journal of Ophthalmology
巻(号)	142(6)
ページ	1064-1066
抄録	Purpose: To investigate the serotypes of adenovirus causing conjunctivitis in Hanoi, Vietnam. Design: Clinical diagnosis of adenoviral conjunctivitis and laboratory-based experimental study. Methods: We collected 21 conjunctival swabs from 21 different patients with a clinical presentation compatible with adenoviral conjunctivitis, in Hanoi, Vietnam. Immunochromatography and real-time polymerase chain reaction (PCR) were performed to detect human adenovirus (HAdV). The sequence of PCR products was analyzed to determine the serotype of HAdV. Results: Of 21 samples, HAdV DNA was detected in 14 samples (66.7%) by real-time PCR. The serotype analysis showed HAdV-8 in 11 samples (78.6%), HAdV-3 in two samples (14.3%), and HAdV-37 in one sample (7.1%). Of 11 HAdV-8 samples, one sample (9.1%) was prototype, and the other 10 samples (90.9%) had identical nucleotide sequence and were identified as a variant of HAdV-8.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
PISSN	0002-9394
関連情報	PMID 17157595
関連情報	URI http://www.sciencedirect.com/science/journal/00029394
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.ajo.2006.07.041