Memory and Decision Making in the Frontal Cortex during Visual Motion Processing for Smooth Pursuit Eye Movements

Shichinohe, Natsuko; Akao, Teppei; Kurkin, Sergei; Fukushima, Junko; Kaneko, Chris R. S.; Fukushima, Kikuro

Memory and Decision Making in the Frontal Cortex during Visual Motion Processing for Smooth Pursuit Eye Movements

Shichinohe, Natsuko; Akao, Teppei; Kurkin, Sergei et al.

Neuron, 2009, 62(5), 717-732

Permalink : https://hdl.handle.net/2115/38756

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アクセス権	open access
URI	https://hdl.handle.net/2115/38756
タイトル	Memory and Decision Making in the Frontal Cortex during Visual Motion Processing for Smooth Pursuit Eye Movements
著者	Shichinohe, Natsuko ; Akao, Teppei ; Kurkin, Sergei ; Fukushima, Junko ; Kaneko, Chris R. S. ; Fukushima, Kikuro
著者名 Shichinohe, Natsuko
著者名 Akao, Teppei
e-Rad_Researcher 00344466 著者名 Kurkin, Sergei
e-Rad_Researcher 40208939 著者名 Fukushima, Junko
著者名 Kaneko, Chris R. S.
e-Rad_Researcher 70091486 著者名 Fukushima, Kikuro
言語	英語
キーワード	Frontal cortex
	Supplementary eye fields
	Smooth pursuit
	Visual motion
	Memory
	Decision-making
	Movement preparation, Monkey
発行日	2009-06-11
出版者	Cell Press
収録物名	Neuron
巻(号)	62(5)
ページ	717-732
抄録	Cortical motor areas are thought to contribute "higher-order processing" but what that processing might include is unknown. Previous studies of the smooth pursuit-related discharge of supplementary eye field (SEF) neurons did not distinguish activity associated with the preparation for pursuit from discharge related to processing or memory of the target motion signals. Using a new, memory-based task, which was designed to separate these components, we show that the SEF contains signals coding retinal image-slip-velocity, memory and assessment of visual motion-direction, the decision of whether or not to pursue, and the preparation for pursuit eye movements. Bilateral muscimol injection into SEF resulted in directional errors in smooth pursuit, errors of whether or not to pursue, and impairment of initial correct eye movements. These results suggest an important role for the SEF in memory and assessment of visual motion-direction and the programming of appropriate pursuit eye movements.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
PISSN	0896-6273
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.neuron.2009.05.010