open access

https://hdl.handle.net/2115/43044

Spatiotemporal properties of eye position signals in the primate central thalamus.

英語

thalamocortical pathways

2007-07

Oxford University Press

Cerebral Cortex

17(7)

1504-1515

Although both sensory and motor signals in multiple cortical areas are modulated by eye position, the origin of eye position signals for cortical neurons remains uncertain. One likely source is the central thalamus which contains neurons sensitive to eye position. Since the central thalamus receives inputs from the brainstem, these neurons may transmit eye position signals arising from the neural integrator or from proprioceptive feedback. However, since the central thalamus also receives inputs from many cortical areas, eye position signals in the central thalamus could come from the cerebral cortex. To clarify these possibilities, spatial and temporal properties of eye position signals in the central thalamus were examined in trained monkeys. Data showed that eye position signals were decomposed into horizontal and vertical components, suggesting that the central thalamus lies within pathways that transmit brainstem eye position signals to the cortex. Further quantitative analyses suggested that two distinct groups of thalamic neurons mediate eye position signals from different subcortical origins, and that the signals are modified dynamically through ascending pathways. Eye position signals through the central thalamus may play essential roles in spatial transformation performed by cortical networks.

学術雑誌論文

Accepted Manuscript

This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Cerebral Cortex following peer review. The definitive publisher-authenticated version [Cerebral Cortex 2007 17(7):1504-1515] is available online at: http://cercor.oxfordjournals.org/cgi/content/full/17/7/1504.

1460-2199

1047-3211