Duration and Booster Effect of Phylactic Response against White Spot Syndrome Virus Infection in Kuruma Shrimp Orally Administrated with Recombinant Viral Proteins, rVP26 and rVP28

Satoh, Jun; Nishizawa, Toyohiko; Yoshimizu, Mamoru

Duration and Booster Effect of Phylactic Response against White Spot Syndrome Virus Infection in Kuruma Shrimp Orally Administrated with Recombinant Viral Proteins, rVP26 and rVP28

Satoh, Jun; Nishizawa, Toyohiko; Yoshimizu, Mamoru

Fish Pathology, 2009, 44(3), 120-127

Permalink : https://hdl.handle.net/2115/43818

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論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/43818
タイトル	Duration and Booster Effect of Phylactic Response against White Spot Syndrome Virus Infection in Kuruma Shrimp Orally Administrated with Recombinant Viral Proteins, rVP26 and rVP28
著者	Satoh, Jun ; Nishizawa, Toyohiko ; Yoshimizu, Mamoru
e-Rad_Researcher 10443350 著者名 Satoh, Jun
e-Rad_Researcher 10222184 著者名 Nishizawa, Toyohiko
e-Rad_Researcher 40122915 著者名 Yoshimizu, Mamoru
言語	英語
キーワード	white spot syndrome virus
	WSSV
	quasi-immune response
	kuruma shrimp
	oral vaccination
	phylaxis
	booster effect
	PRDV
発行日	2009-09
出版者	Japanese Society of Fish Pathology
収録物名	Fish Pathology
収録物名	魚病研究
巻(号)	44(3)
ページ	120-127
抄録	White spot syndrome virus (WSSV: a synonym of penaeid rod-shaped DNA virus, PRDV) is the causative agent of white spot disease (WSD: penaeid acute viremia, PAV), one of the most serious diseases affecting decapod crustaceans around the world. Recently, "quasi-immune response" was found in kuruma shrimp Penaeus japonicus, wherein individuals that naturally survived from WSD showed protection against a rechallenge with WSSV. The phylaxis against WSSV was also inducible by oral vaccination with recombinant WSSV proteins, rVP26 and rVP28. In the present study, kuruma shrimp orally vaccinated with rVPs were sequentially challenged with WSSV to evaluate onset and duration of phylactic response and booster effect. The phylactic response of shrimp against WSSV-challenge peaked at day 45 after the vaccination with rVP26 (RPS: 100%) and at day 55 with rVP28 (RPS: 93%), and decreased within 10-20 days. The phylaxis against WSSV-challenge was boosted by the secondary vaccination with homologous rVPs, but not by those with heterologous rVPs. The peaks of phylactic responses appeared at day 22 after the secondary vaccination more rapidly than those after the primary vaccination. These results demonstrated that the duration of phylaxis induced by oral vaccination with rVPs was relatively short, but could be extended by booster vaccination with homologous rVPs.
資源タイプ	学術雑誌論文
出版タイプ	Version of Record
PISSN	0388-788X
関連情報 (isIdenticalTo)	出版社版DOI https://doi.org/10.3147/jsfp.44.120