Postoperative Bowel Function and Nutritional Status following Distal Pancreatectomy with En-Bloc Celiac Axis Resection

Hirano, Satoshi; Kondo, Satoshi; Tanaka, Eiichi et al.

Digestive Surgery, 2010, 27(3), 212-216

Permalink : https://hdl.handle.net/2115/43838

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論文情報

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アクセス権
open access
URI
https://hdl.handle.net/2115/43838
タイトル
Postoperative Bowel Function and Nutritional Status following Distal Pancreatectomy with En-Bloc Celiac Axis Resection
著者
Hirano, Satoshi ; Kondo, Satoshi ; Tanaka, Eiichi ; Shichinohe, Toshiaki ; Tsuchikawa, Takahiro ; Kato, Kentaro ; Matsumoto, Joe
著者名
Hirano, Satoshi
著者名
Kondo, Satoshi
e-Rad_Researcher
60374279
著者名
Tanaka, Eiichi
著者名
Shichinohe, Toshiaki
著者名
Tsuchikawa, Takahiro
著者名
Kato, Kentaro
著者名
Matsumoto, Joe
言語
英語
キーワード
Pancreatic cancer
Distal pancreatectomy
Postoperative complications
Diarrhea
Nutrition
発行日
2010-08
出版者
Karger
収録物名
Digestive Surgery
巻(号)
27(3)
ページ
212-216
抄録
Background/Aims: Distal pancreatectomy with en bloc celiac axis resection (DP-CAR) is routinely accompanied by complete resection of the bilateral celiac ganglions and the circumferential plexus of the superior mesenteric artery. The postoperative condition including bowel movement and nutritional status, and tolerance to adjuvant chemotherapy has never been studied. Methods: Forty patients who underwent DP-CAR were enrolled in this study. Postoperative bowel function was estimated by the requirement of antidiarrheal agents. Changes of nutritional parameters including body weight and laboratory data for one year after surgery were evaluated. Results: Fifteen (38%) patients needed no anti-diarrheal agent after a median follow-up period of 39 months. Other patients were well controlled for their bowel movement with anti-diarrheal drugs. Thirteen patients who received adjuvant chemotherapy were well tolerated despite the hematologic toxicity in seven patients who received gemcitabine. Postoperative body weight was significantly decreased and reached a plateau value at 3 postoperative months. The values of laboratory data indicating nutritional status were significantly dropped at 1 month after surgery and recovered between 3 and 12 months. Conclusion: The patients who underwent DP-CAR scarcely suffered from intractable diarrhea, and could achieve a feasible nutritional status after surgery, to be able to receive adjuvant chemotherapy.
資源タイプ
学術雑誌論文
出版タイプ
Accepted Manuscript
権利情報
Copyright © 2010 S. Karger AG, Basel
PISSN
0253-4886
関連情報
PMID
20571268
関連情報 (isVersionOf)
出版社版DOI
https://doi.org/10.1159/000265573