Follicular dendritic cell sarcoma of small intestine with aberrant T-cell marker expression

Yamada, Yosuke; Haga, Hironori; Hernandez, Mako; Kubota, Kanako C.; Orii, Fumika; Nagashima, Kazuo; Matsuno, Yoshihiro

Follicular dendritic cell sarcoma of small intestine with aberrant T-cell marker expression

Yamada, Yosuke; Haga, Hironori; Hernandez, Mako et al.

Pathology International, 2009, 59(11), 809-812

Permalink : https://hdl.handle.net/2115/44110

このアイテムのアクセス数:1,471件（2026-02-16 10:53 集計）

閲覧可能ファイル

ファイル	フォーマット	サイズ	閲覧回数	説明
PI59-11_809-812	pdf	500 KB	2,530

論文情報

ファイル出力 EndNote Basic出力 Mendeley出力

アクセス権	open access
URI	https://hdl.handle.net/2115/44110
タイトル	Follicular dendritic cell sarcoma of small intestine with aberrant T-cell marker expression
著者	Yamada, Yosuke ; Haga, Hironori ; Hernandez, Mako ; Kubota, Kanako C. ; Orii, Fumika ; Nagashima, Kazuo ; Matsuno, Yoshihiro
著者名 Yamada, Yosuke
著者名 Haga, Hironori
著者名 Hernandez, Mako
著者名 Kubota, Kanako C.
著者名 Orii, Fumika
著者名 Nagashima, Kazuo
著者名 Matsuno, Yoshihiro
言語	英語
キーワード	dendritic cell sarcoma
	follicular
	lymphoma
	intestine
	small
	T-cell
発行日	2009-11
出版者	Wiley-Blackwell
収録物名	Pathology International
巻(号)	59(11)
ページ	809-812
抄録	Follicular dendritic cell sarcoma (FDCS) is an uncommon neoplasia usually occurring in lymphoid tissue. Herein is present a case of FDCS of the small intestine with positivity for T-cell antigen, simulating T-cell lymphoma. An 82-year-old man consulted a doctor for epigastric pain of one-week duration. Imaging study revealed a mass in the small intestine. Malignant lymphoma was suspected because of high serum levels of soluble interleukin-2 receptor, and resection of the tumor was performed. Microscopically, the tumor was comprised of large pleomorphic cells with reactive small lymphocytes. Most of the nuclei of the tumor cells were round or ovoid-shaped, and some of the tumor cells also showed spindle-shaped nuclei. Although the tumor cells were diffusely positive for CD45RO and CD4 immunohistochemically, negativity for pan-T-cell markers and CD56 were unusual for T-cell lymphoma of intestinal origin. Additional immunohistochemical study demonstrated that the tumor cells were positive for follicular dendritic cell markers including CD23, CD35 and CAN.42, and diagnosis of FDCS was made. To our knowledge, this is the first case of FDCS aberrantly expressing CD45RO, and FDCS expressing T-cell markers can be a pitfall for diagnosis of FDCS.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	The definitive version is available at www.blackwell-synergy.com
PISSN	1320-5463
関連情報	PMID 19883432
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1111/j.1440-1827.2009.02449.x