A parameter study of pencil beam proton dose distributions for the treatment of ocular melanoma utilizing spot scanning

Sutherland, Kenneth; Miyajima, Satoshi; Date, Hiroyuki et al.

Radiological Physics and Technology, 2010, 3(1), 16-22

Permalink : https://hdl.handle.net/2115/46897

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アクセス権
open access
URI
https://hdl.handle.net/2115/46897
タイトル
A parameter study of pencil beam proton dose distributions for the treatment of ocular melanoma utilizing spot scanning
著者
Sutherland, Kenneth ; Miyajima, Satoshi ; Date, Hiroyuki ; Shirato, Hiroki ; Ishikawa, Masayori ; Murakami, Masao ; Yamagiwa, Mitsuru ; Bolton, Paul ; Tajima, Toshiki
著者名
Sutherland, Kenneth
著者名
Miyajima, Satoshi
著者名
Date, Hiroyuki
著者名
Shirato, Hiroki
著者名
Ishikawa, Masayori
著者名
Murakami, Masao
著者名
Yamagiwa, Mitsuru
著者名
Bolton, Paul
著者名
Tajima, Toshiki
言語
英語
キーワード
proton therapy
ocular melanoma
Monte Carlo simulation
laser acceleration
発行日
2010-01
出版者
Springer Japan
収録物名
Radiological Physics and Technology
巻(号)
3(1)
ページ
16-22
抄録
Results of Monte Carlo calculated dose distributions of proton treatment of ocular melanoma are presented. An efficient spot-scanning method utilizing active energy modulation which also minimizes the number of target spots was developed. We simulated various parameter values for the particle energy spread and the pencil-beam diameter in order to determine values suitable for medical treatment. We found that a 2.5-mm-diameter proton beam with a 5% Gaussian energy spread is suitable for treatment of ocular melanoma while preserving vision for the typical case that we simulated. The energy spectra and required proton current were also calculated and are reported. The results are intended to serve as a guideline for a new class of low-cost, compact accelerators.
資源タイプ
学術雑誌論文
出版タイプ
Accepted Manuscript
権利情報
The original final publication is available at www.springerlink.com
PISSN
1865-0333
EISSN
1865-0341
関連情報
PMID
20821097
関連情報 (isVersionOf)
出版社版DOI
https://doi.org/10.1007/s12194-009-0071-4