Synthesis of Cyclic ADP-Carbocylcic-Xylose and its 3′′-OO-Methyl Analogue as Stable and Potent Ca2+-Mobilizing Agents

Kudoh, Takashi; Matsuda, Akira; Shuto, Satoshi et al.

Nucleosides, Nucleotides and Nucleic Acids, 2006, 25(4-6), 583-599

Permalink : https://hdl.handle.net/2115/46970

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アクセス権	open access
URI	https://hdl.handle.net/2115/46970
タイトル	Synthesis of Cyclic ADP-Carbocylcic-Xylose and its 3′′-OO-Methyl Analogue as Stable and Potent Ca2+-Mobilizing Agents
著者	Kudoh, Takashi ; Matsuda, Akira ; Shuto, Satoshi ; Murayama, Takashi ; Ogawa, Yasuo
著者名 Kudoh, Takashi
著者名 Matsuda, Akira
著者名 Shuto, Satoshi
著者名 Murayama, Takashi
著者名 Ogawa, Yasuo
言語	英語
発行日	2006-04
出版者	Taylor & Francis
収録物名	Nucleosides, Nucleotides and Nucleic Acids
巻(号)	25(4-6)
ページ	583-599
抄録	We previously showed that 3”-deoxy-cyclic ADP-carbocyclic-ribose (3”-deoxy-cADPcR, 2) is a stable and highly potent analogue of cyclic ADP-ribose (cADPR, 1), a Ca2+-mobilizing second messenger. From these results, we newly designed another 3”-modified analogues of cADPcR and identified the N1-“xylo”-type carbocyclic analogue, i.e., cADPcX (4), as one of the most potent cADPR-related compounds reported so far.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	This is an electronic version of an article published in Nucleosides, Nucleotides & Nucleic Acids, 25(4/6), 583-599, 2006. Nucleosides, Nucleotides & Nucleic Acids is available online at: http://www.informaworld.com/openurl?genre=article&issn=15257770&volume=25&issue=4-6&spage=583
PISSN	1525-7770
EISSN	1532-2335
関連情報	PMID 16838847
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1080/15257770600685867