Nationwide survey on the epidemiology of syringomyelia in Japan

Sakushima, Ken; Tsuboi, Satoshi; Yabe, Ichiro; Hida, Kazutoshi; Terae, Satoshi; Uehara, Ritei; Nakano, Imaharu; Sasaki, Hidenao

Nationwide survey on the epidemiology of syringomyelia in Japan

Sakushima, Ken; Tsuboi, Satoshi; Yabe, Ichiro et al.

Journal of the Neurological Sciences, 2012, 313(1-2), 147-152

Permalink : https://hdl.handle.net/2115/48600

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アクセス権	open access
URI	https://hdl.handle.net/2115/48600
タイトル	Nationwide survey on the epidemiology of syringomyelia in Japan
著者	Sakushima, Ken ; Tsuboi, Satoshi ; Yabe, Ichiro ; Hida, Kazutoshi ; Terae, Satoshi ; Uehara, Ritei ; Nakano, Imaharu ; Sasaki, Hidenao
著者名 Sakushima, Ken
著者名 Tsuboi, Satoshi
e-Rad_Researcher 60372273 著者名 Yabe, Ichiro
e-Rad_Researcher 10238305 著者名 Hida, Kazutoshi
e-Rad_Researcher 40240634 著者名 Terae, Satoshi
著者名 Uehara, Ritei
著者名 Nakano, Imaharu
e-Rad_Researcher 80281806 著者名 Sasaki, Hidenao
言語	英語
キーワード	Syringomyelia
	Epidemiology
	Nationwide survey
	Magnetic Resonance Imaging
	Postal survey
	Ambulatory prevalence
発行日	2012-02-15
出版者	Elsevier B.V.
収録物名	Journal of the Neurological Sciences
巻(号)	313(1-2)
ページ	147-152
抄録	Background: Syringomyelia is a rare disease characterized by abnormal fluid-filled cavities within the spinal cord, and is associated with Chiari malformations, arachnoiditis, or spinal cord tumors. The widespread availability of magnetic resonance imaging (MRI) in Japan has allowed for easy identification of syrinxes. The aim of this study was to survey the clinicoepidemiological characteristics of syringomyelia in Japan. Methods: A 2-stage postal survey was conducted in late 2009. The first survey aimed to estimate the number of patients with syringomyelia, and the second survey aimed to elucidate clinicoepidemiological characteristics. Diagnosis of syringomyelia was based on the findings of MRI or computed tomographic myelography. Results: In the first survey, we received 2133 responses from 2937 randomly selected departments and collected data of 1215 syringomyelia patients (543 men and 672 women). The total response rate for the first survey was 73%. The estimated prevalence of ambulatory syringomyelia patients in Japan was 1.94 per 100 000. In the second survey, the proportion of asymptomatic syringomyelia patients was 22.7%. Chiari type I malformations and idiopathic syringomyelia were the first and second most common etiologies. Conclusions: Our nationwide survey indicated that widespread MRI availability has contributed to the diagnosis of both asymptomatic and idiopathic cases.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
PISSN	0022-510X
関連情報	PMID 21943925
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.jns.2011.08.045