Validation Study on the Accuracy of Echocardiographic Measurements of Right Ventricular Systolic Function in Pulmonary Hypertension

Sato, Takahiro; Tsujino, Ichizo; Ohira, Hiroshi; Oyama-Manabe, Noriko; Yamada, Asuka; Ito, Yoichi M.; Goto, Chisa; Watanabe, Taku; Sakaue, Shinji; Nishimura, Masaharu

Validation Study on the Accuracy of Echocardiographic Measurements of Right Ventricular Systolic Function in Pulmonary Hypertension

Sato, Takahiro; Tsujino, Ichizo; Ohira, Hiroshi et al.

Journal of the American Society of Echocardiography, 2012, 25(3), 280-286

Permalink : https://hdl.handle.net/2115/48647

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アクセス権	open access
URI	https://hdl.handle.net/2115/48647
タイトル	Validation Study on the Accuracy of Echocardiographic Measurements of Right Ventricular Systolic Function in Pulmonary Hypertension
著者	Sato, Takahiro ; Tsujino, Ichizo ; Ohira, Hiroshi ; Oyama-Manabe, Noriko ; Yamada, Asuka ; Ito, Yoichi M. ; Goto, Chisa ; Watanabe, Taku ; Sakaue, Shinji ; Nishimura, Masaharu
著者名 Sato, Takahiro
e-Rad_Researcher 00344507 著者名 Tsujino, Ichizo
著者名 Ohira, Hiroshi
著者名 Oyama-Manabe, Noriko
著者名 Yamada, Asuka
著者名 Ito, Yoichi M.
著者名 Goto, Chisa
著者名 Watanabe, Taku
著者名 Sakaue, Shinji
著者名 Nishimura, Masaharu
言語	英語
キーワード	Pulmonary hypertension
	Echocardiography
	Right ventricular systolic function
	Tricuspid annular plane systolic excursion
発行日	2012-03
出版者	Mosby
収録物名	Journal of the American Society of Echocardiography
巻(号)	25(3)
ページ	280-286
抄録	Background: Accuracy of echocardiographic parameters of right ventricular (RV) function has not been sufficiently validated in patients with pulmonary hypertension (PH). We attempted to evaluate whether echocardiographic measurements reliably reflect RV systolic function in PH using cardiac magnetic resonance imaging (CMRI)-derived RV ejection fraction (EF) as a gold standard. Materials and Methods: A total of thirty-seven consecutive patients with PH, 20 with pulmonary arterial hypertension, 12 with chronic thromboembolic pulmonary hypertension, and 5 others, were prospectively studied. All patients underwent echocardiography, CMRI and right heart catheterization within a 1-week interval. Associations between 5 echocardiography-derived parameters of RV systolic function and CMRI-derived RVEF were evaluated. Results: All 5 echocardiography-derived parameters were significantly correlated with CMRI-derived RVEF (%RV fractional shortening: r=0.48, p=0.0011; %RV area change: r=0.40, p=0.0083; tricuspid annular plane systolic excursion (TAPSE): r=0.86, p<0.0001, RV myocardial performance index: r=-0.59, p<0.0001; and systolic lateral tricuspid annular motion velocity (TVlat): r=0.63, p<0.0001). When compared with the other indices, TAPSE exhibited the highest correlation coefficient. Of the 5 echocardiographic measurements, only TAPSE significantly predicted CMRI-derived RVEF in multiple regression analysis (p<0.0001). Intra- and interobserver reproducibility was favorable for all 5 indices, and for TAPSE and TVlat was particularly high. Conclusion: Echocardiographic measurements are promising noninvasive indices of RV systolic function in patients with PH. In particular, TAPSE is superior to other indices in accuracy.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
PISSN	0894-7317
関連情報	PMID 22230250
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1016/j.echo.2011.12.012