open access

https://hdl.handle.net/2115/52053

11C-Methionine positron emission tomography may monitor the activity of encephalitis

英語

therapy monitoring

2012-12

Royal Society of Medicine Press

Acta Radiologica

53(10)

1155-1157

Encephalitis is generally diagnosed by clinical symptoms, cerebrospinal fluid examination, and imaging studies including CT, MR imaging and perfusion single photon emission tomography (SPECT). However, the role of positron emission tomography (PET) in diagnosis of encephalitis remains unclear. A 49-year-old woman presenting with coma and elevated inflammatory reaction was diagnosed as having encephalitis according to slow activity on electroencephalogram, broad cortical lesion in MR fluid attenuated inversion recovery image, and increased blood flow demonstrated by SPECT. PET revealed increased accumulation of 11C-methionine (MET) in the affected brain tissues. After the symptom had improved two months later, the accumulation of MET as well as the abnormal findings of MR imaging and SPECT was normalized. This case indicated that MET PET may monitor the activity of encephalitis.

学術雑誌論文

Accepted Manuscript

Acta Radiol, December 2012, 53(10), pp.1155-1157, doi: 10.1258/ar.2012.120382. This is the final draft, after peer-review, of a manuscript published in Acta Radiologica. The definitive version, detailed above, is available online at www.rsmjournals.com.

0284-1851