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論文情報

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アクセス権	open access
URI	https://hdl.handle.net/2115/52989
タイトル	Effects of parabens on apoptosis induced by serum-free medium.
著者	Egawa, Mari ; Aoki, Kentaro ; Sun, Yongkun ; Hosokawa, Toshiyuki ; Saito, Takeshi ; Kurasaki, Masaaki
著者名 Egawa, Mari
著者名 Aoki, Kentaro
著者名 Sun, Yongkun
e-Rad_Researcher 00157025 著者名 Hosokawa, Toshiyuki
e-Rad_Researcher 40153811 著者名 Saito, Takeshi
e-Rad_Researcher 80161727 著者名 Kurasaki, Masaaki
言語	英語
キーワード	PC12 cell
	endocrine disrupter
	food additives
	apoptotic factors
	methylparaben
	butylparaben
発行日	2012-03
出版者	Taylor & Francis
収録物名	Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes
巻(号)	47(3)
ページ	196-204
抄録	Alkyl esters of p-hydroxybenzoic acids (parabens), an endocrine disrupter, are used as preservatives in cosmetics and foods. In this study, to understand the relationship between parabens and differentiation in infants, the effects of parabens on apoptosis induced by serum deprivation in PC12 cells were investigated. In addition, apoptosis-related factors were assayed. As results, a tendency toward enhancement of apoptosis was observed in the cells cultured in the serum-free medium with methylparaben, and this tendency was suggested to be related to the contents of BAD, a pro-apoptotic protein. Butylparaben did not show any tendency to enhance apoptosis.
資源タイプ	学術雑誌論文
出版タイプ	Accepted Manuscript
権利情報	This is an Author's Accepted Manuscript of an article published in Journal of Environmental Science and Health, Part B Pesticides, Food Contaminants, and Agricultural Wastes, Vol. 47, Iss. 3, 2012, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/03601234.2012.634341.
PISSN	0360-1234
EISSN	1532-4109
NCID	AA00697424
関連情報	PMID 22375591
関連情報 (isVersionOf)	出版社版DOI https://doi.org/10.1080/03601234.2012.634341

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